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Avian Neuropeptide Y: Beyond Feed Intake Regulation
Neuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian spec...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028514/ https://www.ncbi.nlm.nih.gov/pubmed/35448669 http://dx.doi.org/10.3390/vetsci9040171 |
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author | Greene, Elizabeth S. Abdelli, Nedra Dridi, Jalila S. Dridi, Sami |
author_facet | Greene, Elizabeth S. Abdelli, Nedra Dridi, Jalila S. Dridi, Sami |
author_sort | Greene, Elizabeth S. |
collection | PubMed |
description | Neuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian species. Indeed, NPY has been shown to be involved in the regulation of feed intake and energy homeostasis by exerting stimulatory effects on appetite and feeding behavior in several species including chickens, rabbits, rats and mouse. More recent studies have shown that this neuropeptide and its receptors are expressed in various peripheral tissues, including the thyroid, heart, spleen, adrenal glands, white adipose tissue, muscle and bone. Although well researched centrally, studies investigating the distribution and function of peripherally expressed NPY in avian (non-mammalian vertebrates) species are very limited. Thus, peripherally expressed NPY merits more consideration and further in-depth exploration to fully elucidate its functions, especially in non-mammalian species. The aim of the current review is to provide an integrated synopsis of both centrally and peripherally expressed NPY, with a special focus on the distribution and function of the latter. |
format | Online Article Text |
id | pubmed-9028514 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90285142022-04-23 Avian Neuropeptide Y: Beyond Feed Intake Regulation Greene, Elizabeth S. Abdelli, Nedra Dridi, Jalila S. Dridi, Sami Vet Sci Review Neuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian species. Indeed, NPY has been shown to be involved in the regulation of feed intake and energy homeostasis by exerting stimulatory effects on appetite and feeding behavior in several species including chickens, rabbits, rats and mouse. More recent studies have shown that this neuropeptide and its receptors are expressed in various peripheral tissues, including the thyroid, heart, spleen, adrenal glands, white adipose tissue, muscle and bone. Although well researched centrally, studies investigating the distribution and function of peripherally expressed NPY in avian (non-mammalian vertebrates) species are very limited. Thus, peripherally expressed NPY merits more consideration and further in-depth exploration to fully elucidate its functions, especially in non-mammalian species. The aim of the current review is to provide an integrated synopsis of both centrally and peripherally expressed NPY, with a special focus on the distribution and function of the latter. MDPI 2022-04-01 /pmc/articles/PMC9028514/ /pubmed/35448669 http://dx.doi.org/10.3390/vetsci9040171 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Greene, Elizabeth S. Abdelli, Nedra Dridi, Jalila S. Dridi, Sami Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title_full | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title_fullStr | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title_full_unstemmed | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title_short | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
title_sort | avian neuropeptide y: beyond feed intake regulation |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028514/ https://www.ncbi.nlm.nih.gov/pubmed/35448669 http://dx.doi.org/10.3390/vetsci9040171 |
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