Cargando…

Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study

Vestibular migraine (VM) is a leading cause of episodic vertigo, affecting up to 1% of the general population. Despite established diagnostic criteria, there is currently no evidence-based approach for acute treatment of VM, with treatment recommendations generally extrapolated from studies on class...

Descripción completa

Detalles Bibliográficos
Autores principales: Rashid, Sk Mamun Ur, Sumaria, Sheetal, Koohi, Nehzat, Arshad, Qadeer, Kaski, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028524/
https://www.ncbi.nlm.nih.gov/pubmed/35447947
http://dx.doi.org/10.3390/brainsci12040415
_version_ 1784691639834378240
author Rashid, Sk Mamun Ur
Sumaria, Sheetal
Koohi, Nehzat
Arshad, Qadeer
Kaski, Diego
author_facet Rashid, Sk Mamun Ur
Sumaria, Sheetal
Koohi, Nehzat
Arshad, Qadeer
Kaski, Diego
author_sort Rashid, Sk Mamun Ur
collection PubMed
description Vestibular migraine (VM) is a leading cause of episodic vertigo, affecting up to 1% of the general population. Despite established diagnostic criteria, there is currently no evidence-based approach for acute treatment of VM, with treatment recommendations generally extrapolated from studies on classical migraine headache. Several small-scale studies have identified flunarizine as a potentially effective prophylactic medication in VM. We conducted a single-centre observational service evaluation study exploring patient experiences of preventative medications over a 28-month period, including flunarizine, for control of VM symptoms. To compare patient experience of flunarizine with other medications, data from patients taking flunarizine were separately analysed. A total of 90% of VM patients taking flunarizine reported symptomatic improvement, compared to only 32% of patients on other medications. Whilst 50% of patients on flunarizine reported side effects. these were not deemed to outweigh the clinical benefits, with most patients deciding to continue treatment. Our data supports the use of flunarizine in VM.
format Online
Article
Text
id pubmed-9028524
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-90285242022-04-23 Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study Rashid, Sk Mamun Ur Sumaria, Sheetal Koohi, Nehzat Arshad, Qadeer Kaski, Diego Brain Sci Communication Vestibular migraine (VM) is a leading cause of episodic vertigo, affecting up to 1% of the general population. Despite established diagnostic criteria, there is currently no evidence-based approach for acute treatment of VM, with treatment recommendations generally extrapolated from studies on classical migraine headache. Several small-scale studies have identified flunarizine as a potentially effective prophylactic medication in VM. We conducted a single-centre observational service evaluation study exploring patient experiences of preventative medications over a 28-month period, including flunarizine, for control of VM symptoms. To compare patient experience of flunarizine with other medications, data from patients taking flunarizine were separately analysed. A total of 90% of VM patients taking flunarizine reported symptomatic improvement, compared to only 32% of patients on other medications. Whilst 50% of patients on flunarizine reported side effects. these were not deemed to outweigh the clinical benefits, with most patients deciding to continue treatment. Our data supports the use of flunarizine in VM. MDPI 2022-03-22 /pmc/articles/PMC9028524/ /pubmed/35447947 http://dx.doi.org/10.3390/brainsci12040415 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Rashid, Sk Mamun Ur
Sumaria, Sheetal
Koohi, Nehzat
Arshad, Qadeer
Kaski, Diego
Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title_full Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title_fullStr Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title_full_unstemmed Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title_short Patient Experience of Flunarizine for Vestibular Migraine: Single Centre Observational Study
title_sort patient experience of flunarizine for vestibular migraine: single centre observational study
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028524/
https://www.ncbi.nlm.nih.gov/pubmed/35447947
http://dx.doi.org/10.3390/brainsci12040415
work_keys_str_mv AT rashidskmamunur patientexperienceofflunarizineforvestibularmigrainesinglecentreobservationalstudy
AT sumariasheetal patientexperienceofflunarizineforvestibularmigrainesinglecentreobservationalstudy
AT koohinehzat patientexperienceofflunarizineforvestibularmigrainesinglecentreobservationalstudy
AT arshadqadeer patientexperienceofflunarizineforvestibularmigrainesinglecentreobservationalstudy
AT kaskidiego patientexperienceofflunarizineforvestibularmigrainesinglecentreobservationalstudy