Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting

Apixaban and rivaroxaban are the two most prescribed direct factor Xa inhibitors. With the increased use of DOACs in real-world settings, safety and efficacy concerns have emerged, particularly regarding their concomitant use with other drugs. Increasing evidence highlights drug–drug interactions wi...

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Detalles Bibliográficos
Autores principales: Lenoir, Camille, Terrier, Jean, Gloor, Yvonne, Gosselin, Pauline, Daali, Youssef, Combescure, Christophe, Desmeules, Jules Alexandre, Samer, Caroline Flora, Reny, Jean-Luc, Rollason, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028714/
https://www.ncbi.nlm.nih.gov/pubmed/35455642
http://dx.doi.org/10.3390/jpm12040526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028714/
https://www.ncbi.nlm.nih.gov/pubmed/35455642
http://dx.doi.org/10.3390/jpm12040526

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