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Intracerebral Infection with E. coli Impairs Spatial Learning and Induces Necrosis of Hippocampal Neurons in the Tg2576 Mouse Model of Alzheimer’s Disease

BACKGROUND: In patients with Alzheimer’s disease (AD), bacterial infections are often associated with a cognitive decline. Animal models of genuine acute infections with viable bacteria which induce deterioration of neurodegenerative diseases are missing. OBJECTIVE: We assessed the effect of an intr...

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Detalles Bibliográficos
Autores principales:	Schütze, Sandra, Döpke, Anika, Kellert, Benedikt, Seele, Jana, Ballüer, Melissa, Bunkowski, Stephanie, Kreutzfeldt, Mario, Brück, Wolfgang, Nau, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028720/ https://www.ncbi.nlm.nih.gov/pubmed/35530117 http://dx.doi.org/10.3233/ADR-210049

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