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Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus

Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The ma...

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Autores principales: Radic, Tomislav, Cigic, Livia, Glavina, Ana, Hrboka, Ana, Druzijanic, Ana, Musa Leko, Ivona, Biocina-Lukenda, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028799/
https://www.ncbi.nlm.nih.gov/pubmed/35448055
http://dx.doi.org/10.3390/dj10040061
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author Radic, Tomislav
Cigic, Livia
Glavina, Ana
Hrboka, Ana
Druzijanic, Ana
Musa Leko, Ivona
Biocina-Lukenda, Dolores
author_facet Radic, Tomislav
Cigic, Livia
Glavina, Ana
Hrboka, Ana
Druzijanic, Ana
Musa Leko, Ivona
Biocina-Lukenda, Dolores
author_sort Radic, Tomislav
collection PubMed
description Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The main aim of this study, due to lack of any other study covering this topic, was to investigate lipid profile and assess CVR in patients with OLP. Materials and Methods: To create a routine lipid profile, we collected triglyceride serum levels, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol from 63 OLP patients and 63 healthy people representing control subjects. For every patient their individual cardiovascular risk was measured. Results: In comparison with the tested control subjects, patients with OLP had all parameters of the lipid profile elevated, with no differences of statistical importance. Furthermore, the experimental (OLP) and control groups shared similar mean values of the lipid profile parameters. Conclusions: The association of OLP with cardiovascular risk was not established and further studies with more subjects involved are required to validate this connection.
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spelling pubmed-90287992022-04-23 Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus Radic, Tomislav Cigic, Livia Glavina, Ana Hrboka, Ana Druzijanic, Ana Musa Leko, Ivona Biocina-Lukenda, Dolores Dent J (Basel) Article Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The main aim of this study, due to lack of any other study covering this topic, was to investigate lipid profile and assess CVR in patients with OLP. Materials and Methods: To create a routine lipid profile, we collected triglyceride serum levels, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol from 63 OLP patients and 63 healthy people representing control subjects. For every patient their individual cardiovascular risk was measured. Results: In comparison with the tested control subjects, patients with OLP had all parameters of the lipid profile elevated, with no differences of statistical importance. Furthermore, the experimental (OLP) and control groups shared similar mean values of the lipid profile parameters. Conclusions: The association of OLP with cardiovascular risk was not established and further studies with more subjects involved are required to validate this connection. MDPI 2022-04-06 /pmc/articles/PMC9028799/ /pubmed/35448055 http://dx.doi.org/10.3390/dj10040061 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Radic, Tomislav
Cigic, Livia
Glavina, Ana
Hrboka, Ana
Druzijanic, Ana
Musa Leko, Ivona
Biocina-Lukenda, Dolores
Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title_full Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title_fullStr Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title_full_unstemmed Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title_short Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus
title_sort lipid profiles and cardiovascular risk in patients with oral lichen planus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028799/
https://www.ncbi.nlm.nih.gov/pubmed/35448055
http://dx.doi.org/10.3390/dj10040061
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