The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway

Background: ANGPTL3 stimulates lipolysis in adipocytes, but the underlying molecular mechanism is yet unknown. The C-terminal fibrinogen-like domain of ANGPTL3 (ANGPTL3-Fld) activates the AKT pathway in endothelial cells. Hence, we evaluated whether ANGPTL3-Fld stimulates lipolysis in adipocytes thr...

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Detalles Bibliográficos
Autores principales: Bini, Simone, Pecce, Valeria, Di Costanzo, Alessia, Polito, Luca, Ghadiri, Ameneh, Minicocci, Ilenia, Tambaro, Federica, Covino, Stella, Arca, Marcello, D’Erasmo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028860/
https://www.ncbi.nlm.nih.gov/pubmed/35454174
http://dx.doi.org/10.3390/biom12040585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028860/
https://www.ncbi.nlm.nih.gov/pubmed/35454174
http://dx.doi.org/10.3390/biom12040585

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