Cargando…

Design, Synthesis, and Molecular Docking Studies of Curcumin Hybrid Conjugates as Potential Therapeutics for Breast Cancer

Curcumin (CUR) has received great attention over the past two decades due to its anticancer, anti-inflammatory, and antioxidant properties. Similarly, Dichloroacetate (DCA), an pyruvate dehydrogenase kinase 1 (PKD1) inhibitor, has gained huge attention as a potential anticancer drug. However, the cl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Panda, Siva S., Tran, Queen L., Rajpurohit, Pragya, Pillai, Girinath G., Thomas, Sean J., Bridges, Allison E., Capito, Jason E., Thangaraju, Muthusamy, Lokeshwar, Bal L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028889/ https://www.ncbi.nlm.nih.gov/pubmed/35455448 http://dx.doi.org/10.3390/ph15040451

Ejemplares similares

Ursolic Acid Analogs as Potential Therapeutics for Cancer
por: Panda, Siva S., et al.
Publicado: (2022)

Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study
por: Khodaverdian, Verjine, et al.
Publicado: (2019)

Molecular docking studies on inhibition of Stat3 dimerization by curcumin natural derivatives and its conjugates with amino acids
por: Kumar, Anil, et al.
Publicado: (2012)

Curcumin Conjugates of Non‐steroidal Anti‐Inflammatory Drugs: Synthesis, Structures, Anti‐proliferative Assays, Computational Docking, and Inflammatory Response
por: Laali, Kenneth K., et al.
Publicado: (2020)

Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties
por: Srour, Aladdin M., et al.
Publicado: (2021)

Modified Curcumins as Potential Drug Candidates for Breast Cancer: An Overview
por: Flint, Abigail L., et al.
Publicado: (2022)

Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs
por: Singh, Rajendra K, et al.
Publicado: (2009)

Proapoptotic Effect and Molecular Docking Analysis of Curcumin–Resveratrol Hybrids in Colorectal Cancer Chemoprevention
por: Moreno-Q, Gustavo, et al.
Publicado: (2022)

Synthesis, Cytotoxicity and Molecular Docking of New Hybrid Compounds by Combination of Curcumin with Oleanolic Acid
por: Sowa-Kasprzak, Katarzyna, et al.
Publicado: (2023)

Molecular docking analysis of curcumin analogues with COX-2
por: Sohilait, Mario Rowan, et al.
Publicado: (2017)

Molecular targeting of renal cell carcinoma by an oral combination
por: Jordan, Andre R., et al.
Publicado: (2020)

Curcumin and fungal infection – commonly available herbs for common female infection
por: Varthya, Shoban Babu, et al.
Publicado: (2020)

The Role of β-Arrestins in Regulating Stem Cell Phenotypes in Normal and Tumorigenic Cells
por: Kallifatidis, Georgios, et al.
Publicado: (2020)

Targeting Mitochondrial Metabolism in Prostate Cancer with Triterpenoids
por: Mamouni, Kenza, et al.
Publicado: (2021)

Molecular docking and dynamics studies of curcumin with COVID-19 proteins
por: Suravajhala, Renuka, et al.
Publicado: (2021)

High-throughput virtual screening and docking studies of matrix protein vp40 of ebola virus
por: Tamilvanan, Thangaraju, et al.
Publicado: (2013)

A Hybrid System for Magnetic Hyperthermia and Drug Delivery: SPION Functionalized by Curcumin Conjugate
por: Lachowicz, Dorota, et al.
Publicado: (2018)

Molecular Oncology of Bladder Cancer from Inception to Modern Perspective
por: Lokeshwar, Soum D., et al.
Publicado: (2022)

Development of a Transparent Transgenic Zebrafish Cellular Phenotype Tg(6xNF-kB:EGFP); Casper(roy(−/−), nacre(−/−)) to Study NF-kB Activity
por: Rajpurohit, Surendra K., et al.
Publicado: (2023)

Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma
por: Wang, Jiaojiao, et al.
Publicado: (2022)

Enhanced Antioxidant Activities of Metal Conjugates of Curcumin Derivatives
por: Dutta, Sabari, et al.
Publicado: (2001)

Curcumin–Sodium Alginate and Curcumin–Chitosan Conjugates as Drug Delivery Systems: An Interesting Rheological Behaviour
por: Cirillo, Giuseppe, et al.
Publicado: (2023)

Nanoparticle Self-Assembled Grain Like Curcumin Conjugated ZnO: Curcumin Conjugation Enhances Removal of Perylene, Fluoranthene, and Chrysene by ZnO
por: Moussawi, Rasha N., et al.
Publicado: (2016)

Folic acid conjugation improves the bioavailability and chemosensitizing efficacy of curcumin-encapsulated PLGA-PEG nanoparticles towards paclitaxel chemotherapy
por: Thulasidasan, Arun Kumar T., et al.
Publicado: (2017)

ARRB1 Regulates Metabolic Reprogramming to Promote Glycolysis in Stem Cell-Like Bladder Cancer Cells
por: Mamouni, Kenza, et al.
Publicado: (2021)

Pegylated Curcumin Derivative: Water-Soluble Conjugates with Antitumor and Antibacterial Activity
por: Yakub, Guldjan, et al.
Publicado: (2022)

Insights from the molecular docking of curcumin to the virulent factors of Helicobacter pylori
por: Srivastava, Akhileshwar Kumar, et al.
Publicado: (2015)

A comparative molecular docking study of curcumin and methotrexate to dihydrofolate reductase
por: Hobani, Yahya, et al.
Publicado: (2017)

Exploring the Mechanism of Curcumin on Retinoblastoma Based on Network Pharmacology and Molecular Docking
por: Wu, Chengfu, et al.
Publicado: (2022)

Novel Curcumin Diclofenac Conjugate Enhanced Curcumin Bioavailability and Efficacy in Streptococcal Cell Wall-induced Arthritis
por: Jain, S. K., et al.
Publicado: (2014)

Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase
por: Srivastava, Jitendra Kumar, et al.
Publicado: (2017)

Curcumin Conjugated Gold Nanoclusters as Perspective Therapeutics for Diabetic Cardiomyopathy
por: Wei, Dong-zhuo, et al.
Publicado: (2021)

Synthesis, DFT Analyses, Antiproliferative Activity, and Molecular Docking Studies of Curcumin Analogues
por: Ahsan, Mohamed Jawed, et al.
Publicado: (2022)

Inverted papilloma presenting as unilateral proptosis: A case report with review of literature
por: Sagar, Poonam, et al.
Publicado: (2019)

The andean anticancer herbal product BIRM causes destabilization of androgen receptor and induces caspase-8 mediated-apoptosis in prostate cancer
por: Shamaladevi, Nagarajarao, et al.
Publicado: (2016)

Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates
por: Panda, Siva S., et al.
Publicado: (2019)

Inhibition of androgen receptor promotes CXC-chemokine receptor 7-mediated prostate cancer cell survival
por: Hoy, James J., et al.
Publicado: (2017)

Bright luminescence from pure DNA-curcumin–based phosphors for bio hybrid light-emitting diodes
por: Reddy, M. Siva Pratap, et al.
Publicado: (2016)

Gelsolin Amyloidogenesis Is Effectively Modulated by Curcumin and Emetine Conjugated PLGA Nanoparticles
por: Srivastava, Ankit, et al.
Publicado: (2015)

Degree-based topological indices and polynomials of hyaluronic acid-curcumin conjugates
por: Ali, Parvez, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ijp6r63gi41v6a9sj3mk8fmdof