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Preclinical Establishment of a Divalent Vaccine against SARS-CoV-2
First-generation vaccines against SARS-CoV-2 do not provide adequate immune protection. Therefore, we engineered a divalent gene construct combining the receptor-binding domain (RBD) of the spike protein and the immunodominant region of the viral nucleocapsid. This fusion protein was produced in eit...
Autores principales: | Hevesi, Zsofia, Gerges, Daniela Anna, Kapps, Sebastian, Freire, Raimundo, Schmidt, Sophie, Pollak, Daniela D., Schmetterer, Klaus, Frey, Tobias, Lang, Rita, Winnicki, Wolfgang, Schmidt, Alice, Harkany, Tibor, Wagner, Ludwig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9028954/ https://www.ncbi.nlm.nih.gov/pubmed/35455265 http://dx.doi.org/10.3390/vaccines10040516 |
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