Both SUMOylation and ubiquitination of TFE3 fusion protein regulated by androgen receptor are the potential target in the therapy of Xp11.2 translocation renal cell carcinoma

BACKGROUND: The aggressiveness of renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 translocation RCC [Xp11.2 tRCC]) is age‐dependent, which is similar to the overall trend of reproductive endocrine hormones. Therefore, this study focused on the effect and pote...

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Detalles Bibliográficos
Autores principales: Liu, Ning, Chen, Yi, Yang, Lei, Shi, Qiancheng, Lu, Yanwen, Ma, Wenliang, Han, Xiaodong, Guo, Hongqian, Li,, Dongmei, Gan,, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029019/
https://www.ncbi.nlm.nih.gov/pubmed/35452181
http://dx.doi.org/10.1002/ctm2.797

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