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Immune Responses in Leishmaniasis: An Overview
Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90 countries in the world. More than 20 Leishmania species cause different forms of leishmaniasis that range in severity from cutaneous lesions to systemic infection. The diversity of leishmaniasis forms is due to...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029249/ https://www.ncbi.nlm.nih.gov/pubmed/35448829 http://dx.doi.org/10.3390/tropicalmed7040054 |
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author | Costa-da-Silva, Ana Caroline Nascimento, Danielle de Oliveira Ferreira, Jesuino R. M. Guimarães-Pinto, Kamila Freire-de-Lima, Leonardo Morrot, Alexandre Decote-Ricardo, Debora Filardy, Alessandra Almeida Freire-de-Lima, Celio Geraldo |
author_facet | Costa-da-Silva, Ana Caroline Nascimento, Danielle de Oliveira Ferreira, Jesuino R. M. Guimarães-Pinto, Kamila Freire-de-Lima, Leonardo Morrot, Alexandre Decote-Ricardo, Debora Filardy, Alessandra Almeida Freire-de-Lima, Celio Geraldo |
author_sort | Costa-da-Silva, Ana Caroline |
collection | PubMed |
description | Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90 countries in the world. More than 20 Leishmania species cause different forms of leishmaniasis that range in severity from cutaneous lesions to systemic infection. The diversity of leishmaniasis forms is due to the species of parasite, vector, environmental and social factors, genetic background, nutritional status, as well as immunocompetence of the host. Here, we discuss the role of the immune system, its molecules, and responses in the establishment, development, and outcome of Leishmaniasis, focusing on innate immune cells and Leishmania major interactions. |
format | Online Article Text |
id | pubmed-9029249 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90292492022-04-23 Immune Responses in Leishmaniasis: An Overview Costa-da-Silva, Ana Caroline Nascimento, Danielle de Oliveira Ferreira, Jesuino R. M. Guimarães-Pinto, Kamila Freire-de-Lima, Leonardo Morrot, Alexandre Decote-Ricardo, Debora Filardy, Alessandra Almeida Freire-de-Lima, Celio Geraldo Trop Med Infect Dis Review Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90 countries in the world. More than 20 Leishmania species cause different forms of leishmaniasis that range in severity from cutaneous lesions to systemic infection. The diversity of leishmaniasis forms is due to the species of parasite, vector, environmental and social factors, genetic background, nutritional status, as well as immunocompetence of the host. Here, we discuss the role of the immune system, its molecules, and responses in the establishment, development, and outcome of Leishmaniasis, focusing on innate immune cells and Leishmania major interactions. MDPI 2022-03-31 /pmc/articles/PMC9029249/ /pubmed/35448829 http://dx.doi.org/10.3390/tropicalmed7040054 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Costa-da-Silva, Ana Caroline Nascimento, Danielle de Oliveira Ferreira, Jesuino R. M. Guimarães-Pinto, Kamila Freire-de-Lima, Leonardo Morrot, Alexandre Decote-Ricardo, Debora Filardy, Alessandra Almeida Freire-de-Lima, Celio Geraldo Immune Responses in Leishmaniasis: An Overview |
title | Immune Responses in Leishmaniasis: An Overview |
title_full | Immune Responses in Leishmaniasis: An Overview |
title_fullStr | Immune Responses in Leishmaniasis: An Overview |
title_full_unstemmed | Immune Responses in Leishmaniasis: An Overview |
title_short | Immune Responses in Leishmaniasis: An Overview |
title_sort | immune responses in leishmaniasis: an overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029249/ https://www.ncbi.nlm.nih.gov/pubmed/35448829 http://dx.doi.org/10.3390/tropicalmed7040054 |
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