A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine

In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, PQP-1, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. PQP-1 exhibited high selectivity, low limit of detection, and a wide pH range. PQP-1 could be successfully applied...

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Detalles Bibliográficos
Autores principales: Yang, Bing, Zhou, Jiahua, Huang, Xu, Chen, Zhongping, Tian, Shu, Shi, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029482/
https://www.ncbi.nlm.nih.gov/pubmed/35455471
http://dx.doi.org/10.3390/ph15040474
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author Yang, Bing
Zhou, Jiahua
Huang, Xu
Chen, Zhongping
Tian, Shu
Shi, Yujun
author_facet Yang, Bing
Zhou, Jiahua
Huang, Xu
Chen, Zhongping
Tian, Shu
Shi, Yujun
author_sort Yang, Bing
collection PubMed
description In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, PQP-1, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. PQP-1 exhibited high selectivity, low limit of detection, and a wide pH range. PQP-1 could be successfully applied for imaging Lys in living cells and in natural mineral water for drinking. We expect that PQP-1 will expand the detection reaction mechanism and the practical biological applications of Lys.
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spelling pubmed-90294822022-04-23 A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine Yang, Bing Zhou, Jiahua Huang, Xu Chen, Zhongping Tian, Shu Shi, Yujun Pharmaceuticals (Basel) Article In this paper, a new pyrroloquinoline-derivative-based fluorescent probe, PQP-1, was prepared for the selective detection of Lys in living cells and natural mineral water for drinking. PQP-1 exhibited high selectivity, low limit of detection, and a wide pH range. PQP-1 could be successfully applied for imaging Lys in living cells and in natural mineral water for drinking. We expect that PQP-1 will expand the detection reaction mechanism and the practical biological applications of Lys. MDPI 2022-04-13 /pmc/articles/PMC9029482/ /pubmed/35455471 http://dx.doi.org/10.3390/ph15040474 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Bing
Zhou, Jiahua
Huang, Xu
Chen, Zhongping
Tian, Shu
Shi, Yujun
A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title_full A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title_fullStr A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title_full_unstemmed A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title_short A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine
title_sort new pyrroloquinoline-derivative-based fluorescent probe for the selective detection and cell imaging of lysine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029482/
https://www.ncbi.nlm.nih.gov/pubmed/35455471
http://dx.doi.org/10.3390/ph15040474
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