Peptide LCGA-17 Attenuates Behavioral and Neurochemical Deficits in Rodent Models of PTSD and Depression

We have previously described the LCGA-17 peptide as a novel anxiolytic and antidepressant candidate that acts through the α2δ VGCC (voltage-gated calcium channel) subunit with putative synergism with GABA-A receptors. The current study tested the potential efficacy of acute and chronic intranasal (i...

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Detalles Bibliográficos
Autores principales: Malyshev, Anton V., Sukhanova, Iuliia A., Ushakova, Valeria M., Zorkina, Yana A., Abramova, Olga V., Morozova, Anna Y., Zubkov, Eugene A., Mitkin, Nikita A., Pavshintsev, Vsevolod V., Doronin, Igor I., Gedzun, Vasilina R., Babkin, Gennady A., Sanchez, Sergio A., Baker, Miah D., Haile, Colin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029485/
https://www.ncbi.nlm.nih.gov/pubmed/35455459
http://dx.doi.org/10.3390/ph15040462

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