α-Synuclein at the Presynaptic Axon Terminal as a Double-Edged Sword

α-synuclein (α-syn) is a presynaptic, lipid-binding protein strongly associated with the neuropathology observed in Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and Alzheimer’s Disease (AD). In normal physiology, α-syn plays a pivotal role in facilitating endocytosis and exocytosis. In...

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Detalles Bibliográficos
Autores principales: Tan, Li Yang, Tang, Kwan Hou, Lim, Lynette Yu You, Ong, Jia Xin, Park, Hyokeun, Jung, Sangyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029495/
https://www.ncbi.nlm.nih.gov/pubmed/35454096
http://dx.doi.org/10.3390/biom12040507

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