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Concurrent Gene Insertion, Deletion, and Inversion during the Construction of a Novel Attenuated BoHV-1 Using CRISPR/Cas9 Genome Editing

Bovine herpesvirus type I (BoHV-1) is an important pathogen that causes respiratory disease in bovines. The disease is prevalent worldwide, causing huge economic losses to the cattle industry. Gene-deficient vaccines with immunological markers to distinguish them from wild-type infections have becom...

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Detalles Bibliográficos
Autores principales:	Liu, Chun-Yu, Jin, Ming, Guo, Hao, Zhao, Hong-Zhe, Hou, Li-Na, Yang, Yang, Wen, Yong-Jun, Wang, Feng-Xue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029512/ https://www.ncbi.nlm.nih.gov/pubmed/35448664 http://dx.doi.org/10.3390/vetsci9040166

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