Recent Advances in Synergistic Antitumor Effects Exploited from the Inhibition of Ataxia Telangiectasia and RAD3-Related Protein Kinase (ATR)

As one of the key phosphatidylinositol 3-kinase-related kinases (PIKKs) family members, ataxia telangiectasia and RAD3-related protein kinase (ATR) is crucial in maintaining mammalian cell genomic integrity in DNA damage response (DDR) and repair pathways. Dysregulation of ATR has been found across...

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Detalles Bibliográficos
Autores principales: Wang, Li-Wei, Jiang, Songwei, Yuan, Ying-Hui, Duan, Jilong, Mao, Nian-Dong, Hui, Zi, Bai, Renren, Xie, Tian, Ye, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029554/
https://www.ncbi.nlm.nih.gov/pubmed/35458687
http://dx.doi.org/10.3390/molecules27082491

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