Subacute Sclerosing Panencephalitis in Children: The Archetype of Non-Vaccination

Subacute sclerosing panencephalitis (SSPE) is a late complication of measles virus infection that occurs in previously healthy children. This disease has no specific cure and is associated with a high degree of disability and mortality. In recent years, there has been an increase in its incidence in...

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Detalles Bibliográficos
Autores principales: Papetti, Laura, Amodeo, Maria Elisa, Sabatini, Letizia, Baggieri, Melissa, Capuano, Alessandro, Graziola, Federica, Marchi, Antonella, Bucci, Paola, D’Ugo, Emilio, Kojouri, Maedeh, Gioacchini, Silvia, Marras, Carlo Efisio, Nucci, Carlotta Ginevra, Ursitti, Fabiana, Sforza, Giorgia, Ferilli, Michela Ada Noris, Monte, Gabriele, Moavero, Romina, Vigevano, Federico, Valeriani, Massimiliano, Magurano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029616/
https://www.ncbi.nlm.nih.gov/pubmed/35458463
http://dx.doi.org/10.3390/v14040733
Descripción
Sumario:Subacute sclerosing panencephalitis (SSPE) is a late complication of measles virus infection that occurs in previously healthy children. This disease has no specific cure and is associated with a high degree of disability and mortality. In recent years, there has been an increase in its incidence in relation to a reduction in vaccination adherence, accentuated by the COVID-19 pandemic. In this article, we take stock of the current evidence on SSPE and report our personal clinical experience. We emphasise that, to date, the only effective protection strategy against this disease is vaccination against the measles virus.

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