Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil

The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic survei...

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Detalles Bibliográficos
Autores principales: Padilha, Dayane Azevedo, Benetti Filho, Vilmar, Moreira, Renato Simões, Soratto, Tatiany Aparecida Teixeira, Maia, Guilherme Augusto, Christoff, Ana Paula, Barazzetti, Fernando Hartmann, Schörner, Marcos André, Ferrari, Fernanda Luiza, Martins, Carolina Leite, Kawagoe, Eric Kazuo, Wachter, Julia Kinetz, Sachet, Paula, Baptistella, Antuani Rafael, Schlindwein, Aline Daiane, Coelho, Bruna Kellet, Fernandes, Sandra Bianchini, Rovaris, Darcita Buerger, Debiasi dos Anjos, Marlei Pickler, Melo, Fernanda Rosene, Bittencourt, Bianca, Cunha, Sthefani, Meneghetti, Karine Lena, Wendt, Nestor, Madaloz, Tâmela Zamboni, Rodrigues, Marcus Vinícius Duarte, Souza, Doris Sobral Marques, de Moraes, Milene Höehr, Baptista, Rodrigo de Paula, Toledo-Silva, Guilherme, Razzera, Guilherme, Grisard, Edmundo Carlos, Stoco, Patricia Hermes, de Oliveira, Luiz Felipe Valter, Bazzo, Maria Luiza, Fongaro, Gislaine, Wagner, Glauber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029728/
https://www.ncbi.nlm.nih.gov/pubmed/35458424
http://dx.doi.org/10.3390/v14040695
Descripción
Sumario:The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which the Gamma and related lineages were predominant in the second pandemic wave within SC. A regionalization of P.1-like-II in the Western SC region was observed, concomitant to the increase in cases, mortality, and the case fatality rate (CFR) index. This is the first evidence of the regionalization of the SARS-CoV-2 transmission in SC and it highlights the importance of tracking the variants, dispersion, and impact of SARS-CoV-2 on the public health systems.

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