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Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil
The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic survei...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029728/ https://www.ncbi.nlm.nih.gov/pubmed/35458424 http://dx.doi.org/10.3390/v14040695 |
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| author | Padilha, Dayane Azevedo Benetti Filho, Vilmar Moreira, Renato Simões Soratto, Tatiany Aparecida Teixeira Maia, Guilherme Augusto Christoff, Ana Paula Barazzetti, Fernando Hartmann Schörner, Marcos André Ferrari, Fernanda Luiza Martins, Carolina Leite Kawagoe, Eric Kazuo Wachter, Julia Kinetz Sachet, Paula Baptistella, Antuani Rafael Schlindwein, Aline Daiane Coelho, Bruna Kellet Fernandes, Sandra Bianchini Rovaris, Darcita Buerger Debiasi dos Anjos, Marlei Pickler Melo, Fernanda Rosene Bittencourt, Bianca Cunha, Sthefani Meneghetti, Karine Lena Wendt, Nestor Madaloz, Tâmela Zamboni Rodrigues, Marcus Vinícius Duarte Souza, Doris Sobral Marques de Moraes, Milene Höehr Baptista, Rodrigo de Paula Toledo-Silva, Guilherme Razzera, Guilherme Grisard, Edmundo Carlos Stoco, Patricia Hermes de Oliveira, Luiz Felipe Valter Bazzo, Maria Luiza Fongaro, Gislaine Wagner, Glauber |
| author_facet | Padilha, Dayane Azevedo Benetti Filho, Vilmar Moreira, Renato Simões Soratto, Tatiany Aparecida Teixeira Maia, Guilherme Augusto Christoff, Ana Paula Barazzetti, Fernando Hartmann Schörner, Marcos André Ferrari, Fernanda Luiza Martins, Carolina Leite Kawagoe, Eric Kazuo Wachter, Julia Kinetz Sachet, Paula Baptistella, Antuani Rafael Schlindwein, Aline Daiane Coelho, Bruna Kellet Fernandes, Sandra Bianchini Rovaris, Darcita Buerger Debiasi dos Anjos, Marlei Pickler Melo, Fernanda Rosene Bittencourt, Bianca Cunha, Sthefani Meneghetti, Karine Lena Wendt, Nestor Madaloz, Tâmela Zamboni Rodrigues, Marcus Vinícius Duarte Souza, Doris Sobral Marques de Moraes, Milene Höehr Baptista, Rodrigo de Paula Toledo-Silva, Guilherme Razzera, Guilherme Grisard, Edmundo Carlos Stoco, Patricia Hermes de Oliveira, Luiz Felipe Valter Bazzo, Maria Luiza Fongaro, Gislaine Wagner, Glauber |
| author_sort | Padilha, Dayane Azevedo |
| collection | PubMed |
| description | The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which the Gamma and related lineages were predominant in the second pandemic wave within SC. A regionalization of P.1-like-II in the Western SC region was observed, concomitant to the increase in cases, mortality, and the case fatality rate (CFR) index. This is the first evidence of the regionalization of the SARS-CoV-2 transmission in SC and it highlights the importance of tracking the variants, dispersion, and impact of SARS-CoV-2 on the public health systems. |
| format | Online Article Text |
| id | pubmed-9029728 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-90297282022-04-23 Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil Padilha, Dayane Azevedo Benetti Filho, Vilmar Moreira, Renato Simões Soratto, Tatiany Aparecida Teixeira Maia, Guilherme Augusto Christoff, Ana Paula Barazzetti, Fernando Hartmann Schörner, Marcos André Ferrari, Fernanda Luiza Martins, Carolina Leite Kawagoe, Eric Kazuo Wachter, Julia Kinetz Sachet, Paula Baptistella, Antuani Rafael Schlindwein, Aline Daiane Coelho, Bruna Kellet Fernandes, Sandra Bianchini Rovaris, Darcita Buerger Debiasi dos Anjos, Marlei Pickler Melo, Fernanda Rosene Bittencourt, Bianca Cunha, Sthefani Meneghetti, Karine Lena Wendt, Nestor Madaloz, Tâmela Zamboni Rodrigues, Marcus Vinícius Duarte Souza, Doris Sobral Marques de Moraes, Milene Höehr Baptista, Rodrigo de Paula Toledo-Silva, Guilherme Razzera, Guilherme Grisard, Edmundo Carlos Stoco, Patricia Hermes de Oliveira, Luiz Felipe Valter Bazzo, Maria Luiza Fongaro, Gislaine Wagner, Glauber Viruses Article The western mesoregion of the state of Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by the COVID-19 pandemic in early 2021. This study aimed to evaluate the dynamics of the SARS-CoV-2 virus spreading patterns in the SC state from March 2020 to April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which the Gamma and related lineages were predominant in the second pandemic wave within SC. A regionalization of P.1-like-II in the Western SC region was observed, concomitant to the increase in cases, mortality, and the case fatality rate (CFR) index. This is the first evidence of the regionalization of the SARS-CoV-2 transmission in SC and it highlights the importance of tracking the variants, dispersion, and impact of SARS-CoV-2 on the public health systems. MDPI 2022-03-27 /pmc/articles/PMC9029728/ /pubmed/35458424 http://dx.doi.org/10.3390/v14040695 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Padilha, Dayane Azevedo Benetti Filho, Vilmar Moreira, Renato Simões Soratto, Tatiany Aparecida Teixeira Maia, Guilherme Augusto Christoff, Ana Paula Barazzetti, Fernando Hartmann Schörner, Marcos André Ferrari, Fernanda Luiza Martins, Carolina Leite Kawagoe, Eric Kazuo Wachter, Julia Kinetz Sachet, Paula Baptistella, Antuani Rafael Schlindwein, Aline Daiane Coelho, Bruna Kellet Fernandes, Sandra Bianchini Rovaris, Darcita Buerger Debiasi dos Anjos, Marlei Pickler Melo, Fernanda Rosene Bittencourt, Bianca Cunha, Sthefani Meneghetti, Karine Lena Wendt, Nestor Madaloz, Tâmela Zamboni Rodrigues, Marcus Vinícius Duarte Souza, Doris Sobral Marques de Moraes, Milene Höehr Baptista, Rodrigo de Paula Toledo-Silva, Guilherme Razzera, Guilherme Grisard, Edmundo Carlos Stoco, Patricia Hermes de Oliveira, Luiz Felipe Valter Bazzo, Maria Luiza Fongaro, Gislaine Wagner, Glauber Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title | Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title_full | Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title_fullStr | Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title_full_unstemmed | Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title_short | Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil |
| title_sort | emergence of two distinct sars-cov-2 gamma variants and the rapid spread of p.1-like-ii sars-cov-2 during the second wave of covid-19 in santa catarina, southern brazil |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029728/ https://www.ncbi.nlm.nih.gov/pubmed/35458424 http://dx.doi.org/10.3390/v14040695 |
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