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A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study
There is a wide variation in the development and course of erectile dysfunction (ED) in men, which confirms the need for prospective studies. We conducted a cross-sectional analysis among the general male population at the baseline (n = 359) and in a follow-up survey (n = 218) 12 years later. The pr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029758/ https://www.ncbi.nlm.nih.gov/pubmed/35456238 http://dx.doi.org/10.3390/jcm11082146 |
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author | Saramies, Jouko Koiranen, Markku Auvinen, Juha Uusitalo, Hannu Hussi, Esko Becker, Sebastian Keinänen-Kiukaanniemi, Sirkka Tuomilehto, Jaakko Suija, Kadri |
author_facet | Saramies, Jouko Koiranen, Markku Auvinen, Juha Uusitalo, Hannu Hussi, Esko Becker, Sebastian Keinänen-Kiukaanniemi, Sirkka Tuomilehto, Jaakko Suija, Kadri |
author_sort | Saramies, Jouko |
collection | PubMed |
description | There is a wide variation in the development and course of erectile dysfunction (ED) in men, which confirms the need for prospective studies. We conducted a cross-sectional analysis among the general male population at the baseline (n = 359) and in a follow-up survey (n = 218) 12 years later. The prospective 12-year study included 189 men. ED was assessed using the International Index of Erectile Function questionnaire. The mean age of the participants was 62.0 years at the baseline, while at the 12-year follow-up it was 71.6 years. The crude prevalence of ED was 61.6% at the baseline and 78.9% at the follow-up, and the prevalence tended to increase with age. All of the men aged 75 years or more had at least mild ED. The incidence of ED in every thousand person years was 53.5. A total of 54.5% of the men experienced ED progression, while 39.2% reported no changes in erectile function, and 6.3% experienced ED regression during the 12-year study. The likelihood of ED progression was higher in the older compared with younger age group (odds ratio, OR 5.2 (95% CI: 1.1–26.2)), and the likelihood of ED regression was lower among men with increased depression symptoms (OR 0.3 (95% CI: 0.1–0.6)) and among men with a decreased interest in their sexual life (OR 0.1 (95% CI: 0.0–0.6)). Lifestyle factors such as the consumption of alcohol and smoking were not significantly associated with ED. |
format | Online Article Text |
id | pubmed-9029758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90297582022-04-23 A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study Saramies, Jouko Koiranen, Markku Auvinen, Juha Uusitalo, Hannu Hussi, Esko Becker, Sebastian Keinänen-Kiukaanniemi, Sirkka Tuomilehto, Jaakko Suija, Kadri J Clin Med Article There is a wide variation in the development and course of erectile dysfunction (ED) in men, which confirms the need for prospective studies. We conducted a cross-sectional analysis among the general male population at the baseline (n = 359) and in a follow-up survey (n = 218) 12 years later. The prospective 12-year study included 189 men. ED was assessed using the International Index of Erectile Function questionnaire. The mean age of the participants was 62.0 years at the baseline, while at the 12-year follow-up it was 71.6 years. The crude prevalence of ED was 61.6% at the baseline and 78.9% at the follow-up, and the prevalence tended to increase with age. All of the men aged 75 years or more had at least mild ED. The incidence of ED in every thousand person years was 53.5. A total of 54.5% of the men experienced ED progression, while 39.2% reported no changes in erectile function, and 6.3% experienced ED regression during the 12-year study. The likelihood of ED progression was higher in the older compared with younger age group (odds ratio, OR 5.2 (95% CI: 1.1–26.2)), and the likelihood of ED regression was lower among men with increased depression symptoms (OR 0.3 (95% CI: 0.1–0.6)) and among men with a decreased interest in their sexual life (OR 0.1 (95% CI: 0.0–0.6)). Lifestyle factors such as the consumption of alcohol and smoking were not significantly associated with ED. MDPI 2022-04-12 /pmc/articles/PMC9029758/ /pubmed/35456238 http://dx.doi.org/10.3390/jcm11082146 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saramies, Jouko Koiranen, Markku Auvinen, Juha Uusitalo, Hannu Hussi, Esko Becker, Sebastian Keinänen-Kiukaanniemi, Sirkka Tuomilehto, Jaakko Suija, Kadri A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title | A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title_full | A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title_fullStr | A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title_full_unstemmed | A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title_short | A Natural History of Erectile Dysfunction in Elderly Men: A Population-Based, Twelve-Year Prospective Study |
title_sort | natural history of erectile dysfunction in elderly men: a population-based, twelve-year prospective study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029758/ https://www.ncbi.nlm.nih.gov/pubmed/35456238 http://dx.doi.org/10.3390/jcm11082146 |
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