Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells

Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows a high co-localization with mitochondria, and it has been demonstrated to be involved in the homeostasis of key processes within the organel...

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Detalles Bibliográficos
Autores principales: Hambardikar, Vedangi, Guitart-Mampel, Mariona, Scoma, Ernest R., Urquiza, Pedro, Nagana, Gowda G. A., Raftery, Daniel, Collins, John A., Solesio, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029763/
https://www.ncbi.nlm.nih.gov/pubmed/35453370
http://dx.doi.org/10.3390/antiox11040685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029763/
https://www.ncbi.nlm.nih.gov/pubmed/35453370
http://dx.doi.org/10.3390/antiox11040685

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