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Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells
Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows a high co-localization with mitochondria, and it has been demonstrated to be involved in the homeostasis of key processes within the organel...
Autores principales: | Hambardikar, Vedangi, Guitart-Mampel, Mariona, Scoma, Ernest R., Urquiza, Pedro, Nagana, Gowda G. A., Raftery, Daniel, Collins, John A., Solesio, Maria E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029763/ https://www.ncbi.nlm.nih.gov/pubmed/35453370 http://dx.doi.org/10.3390/antiox11040685 |
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