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Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections
The extensive use of antibiotics has contributed to the current antibiotic resistance crisis. Livestock infections of Salmonella spp, Clostridium spp. and E. coli antimicrobial-resistant bacteria represent a public threat to human and animal health. To reduce the incidence of these zoonoses, essenti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029798/ https://www.ncbi.nlm.nih.gov/pubmed/35456873 http://dx.doi.org/10.3390/microorganisms10040822 |
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author | Mariotti, Melinda Lombardini, Giulia Rizzo, Silvia Scarafile, Donatella Modesto, Monica Truzzi, Eleonora Benvenuti, Stefania Elmi, Alberto Bertocchi, Martina Fiorentini, Laura Gambi, Lorenzo Scozzoli, Maurizio Mattarelli, Paola |
author_facet | Mariotti, Melinda Lombardini, Giulia Rizzo, Silvia Scarafile, Donatella Modesto, Monica Truzzi, Eleonora Benvenuti, Stefania Elmi, Alberto Bertocchi, Martina Fiorentini, Laura Gambi, Lorenzo Scozzoli, Maurizio Mattarelli, Paola |
author_sort | Mariotti, Melinda |
collection | PubMed |
description | The extensive use of antibiotics has contributed to the current antibiotic resistance crisis. Livestock infections of Salmonella spp, Clostridium spp. and E. coli antimicrobial-resistant bacteria represent a public threat to human and animal health. To reduce the incidence of these zoonoses, essential oils (EOs) could be effective antibiotic alternatives. This study aims at identifying EOs safe for use, effective both in complementary therapy and in the environmental sanitization of intensive farming. Natural products were chemo-characterized by gas chromatography. Three S. Typhimurium, three C. perfringens and four E. coli strains isolated from poultry and swine farms were used to assess the antimicrobial properties of nine EOs and a modified GR-OLI (mGR-OLI). The toxicity of the most effective ones (Cinnamomum zeylanicum, Cz; Origanum vulgare, Ov) was also evaluated on porcine spermatozoa and Galleria mellonella larvae. Cz, Ov and mGR-OLI showed the strongest antimicrobial activity; their volatile components were also able to significantly inhibit the growth of tested strains. In vitro, Ov toxicity was slightly lower than Cz, while it showed no toxicity on G. mellonella larvae. In conclusion, the study confirms the importance of evaluating natural products to consolidate the idea of safe EO applications in reducing and preventing intensive livestock infections. |
format | Online Article Text |
id | pubmed-9029798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90297982022-04-23 Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections Mariotti, Melinda Lombardini, Giulia Rizzo, Silvia Scarafile, Donatella Modesto, Monica Truzzi, Eleonora Benvenuti, Stefania Elmi, Alberto Bertocchi, Martina Fiorentini, Laura Gambi, Lorenzo Scozzoli, Maurizio Mattarelli, Paola Microorganisms Article The extensive use of antibiotics has contributed to the current antibiotic resistance crisis. Livestock infections of Salmonella spp, Clostridium spp. and E. coli antimicrobial-resistant bacteria represent a public threat to human and animal health. To reduce the incidence of these zoonoses, essential oils (EOs) could be effective antibiotic alternatives. This study aims at identifying EOs safe for use, effective both in complementary therapy and in the environmental sanitization of intensive farming. Natural products were chemo-characterized by gas chromatography. Three S. Typhimurium, three C. perfringens and four E. coli strains isolated from poultry and swine farms were used to assess the antimicrobial properties of nine EOs and a modified GR-OLI (mGR-OLI). The toxicity of the most effective ones (Cinnamomum zeylanicum, Cz; Origanum vulgare, Ov) was also evaluated on porcine spermatozoa and Galleria mellonella larvae. Cz, Ov and mGR-OLI showed the strongest antimicrobial activity; their volatile components were also able to significantly inhibit the growth of tested strains. In vitro, Ov toxicity was slightly lower than Cz, while it showed no toxicity on G. mellonella larvae. In conclusion, the study confirms the importance of evaluating natural products to consolidate the idea of safe EO applications in reducing and preventing intensive livestock infections. MDPI 2022-04-15 /pmc/articles/PMC9029798/ /pubmed/35456873 http://dx.doi.org/10.3390/microorganisms10040822 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mariotti, Melinda Lombardini, Giulia Rizzo, Silvia Scarafile, Donatella Modesto, Monica Truzzi, Eleonora Benvenuti, Stefania Elmi, Alberto Bertocchi, Martina Fiorentini, Laura Gambi, Lorenzo Scozzoli, Maurizio Mattarelli, Paola Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title | Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title_full | Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title_fullStr | Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title_full_unstemmed | Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title_short | Potential Applications of Essential Oils for Environmental Sanitization and Antimicrobial Treatment of Intensive Livestock Infections |
title_sort | potential applications of essential oils for environmental sanitization and antimicrobial treatment of intensive livestock infections |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029798/ https://www.ncbi.nlm.nih.gov/pubmed/35456873 http://dx.doi.org/10.3390/microorganisms10040822 |
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