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Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline

The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE co...

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Autor principal: Ścibior, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029821/
https://www.ncbi.nlm.nih.gov/pubmed/35453475
http://dx.doi.org/10.3390/antiox11040790
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author Ścibior, Agnieszka
author_facet Ścibior, Agnieszka
author_sort Ścibior, Agnieszka
collection PubMed
description The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action.
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spelling pubmed-90298212022-04-23 Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline Ścibior, Agnieszka Antioxidants (Basel) Review The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action. MDPI 2022-04-17 /pmc/articles/PMC9029821/ /pubmed/35453475 http://dx.doi.org/10.3390/antiox11040790 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ścibior, Agnieszka
Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_full Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_fullStr Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_full_unstemmed Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_short Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
title_sort overview of research on vanadium-quercetin complexes with a historical outline
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029821/
https://www.ncbi.nlm.nih.gov/pubmed/35453475
http://dx.doi.org/10.3390/antiox11040790
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