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Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline
The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE co...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029821/ https://www.ncbi.nlm.nih.gov/pubmed/35453475 http://dx.doi.org/10.3390/antiox11040790 |
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author | Ścibior, Agnieszka |
author_facet | Ścibior, Agnieszka |
author_sort | Ścibior, Agnieszka |
collection | PubMed |
description | The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action. |
format | Online Article Text |
id | pubmed-9029821 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90298212022-04-23 Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline Ścibior, Agnieszka Antioxidants (Basel) Review The present review was conducted to gather the available literature on some issues related to vanadium-quercetin (V-QUE) complexes. It was aimed at collecting data from in vitro and in vivo studies on the biological activity, behavior, antioxidant properties, and radical scavenging power of V-QUE complexes. The analysis of relevant findings allowed summarizing the evidence for the antidiabetic and anticarcinogenic potential of V-QUE complexes and suggested that they could serve as pharmacological agents for diabetes and cancer. These data together with other well-documented biological properties of V and QUE (common for both), which are briefly summarized in this review as well, may lay the groundwork for new therapeutic treatments and further research on a novel class of pharmaceutical molecules with better therapeutic performance. Simultaneously, the results compiled in this report point to the need for further studies on complexation of V with flavonoids to gain further insight into their behavior, identify species responsible for their physiological activity, and fully understand their mechanism of action. MDPI 2022-04-17 /pmc/articles/PMC9029821/ /pubmed/35453475 http://dx.doi.org/10.3390/antiox11040790 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ścibior, Agnieszka Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_full | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_fullStr | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_full_unstemmed | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_short | Overview of Research on Vanadium-Quercetin Complexes with a Historical Outline |
title_sort | overview of research on vanadium-quercetin complexes with a historical outline |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029821/ https://www.ncbi.nlm.nih.gov/pubmed/35453475 http://dx.doi.org/10.3390/antiox11040790 |
work_keys_str_mv | AT scibioragnieszka overviewofresearchonvanadiumquercetincomplexeswithahistoricaloutline |