Comparative Evaluation of Six SARS-CoV-2 Real-Time RT-PCR Diagnostic Approaches Shows Substantial Genomic Variant–Dependent Intra- and Inter-Test Variability, Poor Interchangeability of Cycle Threshold and Complementary Turn-Around Times

Several professional societies advise against using real-time Reverse-Transcription PCR (rtRT-PCR) cycle threshold (Ct) values to guide clinical decisions. We comparatively assessed the variability of Ct values generated by six diagnostic approaches by testing serial dilutions of well-characterized...

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Detalles Bibliográficos
Autores principales: Kogoj, Rok, Korva, Misa, Knap, Nataša, Resman Rus, Katarina, Pozvek, Patricija, Avšič-Županc, Tatjana, Poljak, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029830/
https://www.ncbi.nlm.nih.gov/pubmed/35456137
http://dx.doi.org/10.3390/pathogens11040462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029830/
https://www.ncbi.nlm.nih.gov/pubmed/35456137
http://dx.doi.org/10.3390/pathogens11040462

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