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Comparative Evaluation of Six SARS-CoV-2 Real-Time RT-PCR Diagnostic Approaches Shows Substantial Genomic Variant–Dependent Intra- and Inter-Test Variability, Poor Interchangeability of Cycle Threshold and Complementary Turn-Around Times
Several professional societies advise against using real-time Reverse-Transcription PCR (rtRT-PCR) cycle threshold (Ct) values to guide clinical decisions. We comparatively assessed the variability of Ct values generated by six diagnostic approaches by testing serial dilutions of well-characterized...
Autores principales: | Kogoj, Rok, Korva, Misa, Knap, Nataša, Resman Rus, Katarina, Pozvek, Patricija, Avšič-Županc, Tatjana, Poljak, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029830/ https://www.ncbi.nlm.nih.gov/pubmed/35456137 http://dx.doi.org/10.3390/pathogens11040462 |
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