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New α-galactosidase-inhibiting aminohydroxycyclopentanes

A set of cyclopentanoid α-galactosidase ligands was prepared from a partially protected ω-eno-aldose via a reliable (2 + 3)-cycloaddition protocol with slightly modified conditions. The obtained N-benzylisoxazolidine ring was selectively opened and the configuration of the hydroxymethylgroup was inv...

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Detalles Bibliográficos
Autores principales:	Weber, Patrick, Fischer, Roland, Nasseri, Seyed A., Stütz, Arnold E., Thonhofer, Martin, Withers, Stephen G., Wolfsgruber, Andreas, Wrodnigg, Tanja M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029992/ https://www.ncbi.nlm.nih.gov/pubmed/35481199 http://dx.doi.org/10.1039/d1ra02507d

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