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Mycobacterium bovis PknG R242P Mutation Results in Structural Changes with Enhanced Virulence in the Mouse Model of Infection
Mycobacterium bovis is the causative agent of tuberculosis in domestic and wild animal species and sometimes in humans, presenting variable degrees of pathogenicity. It is known that PknG is involved in the first steps of Mycobacterium tuberculosis macrophage infection and immune evasion. We questio...
Autores principales: | de Oliveira, Fábio Muniz, Procopio, Victor Oliveira, de Lima Menezes, Gabriela, da Silva, Roosevelt Alves, Kipnis, André, Junqueira-Kipnis, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030157/ https://www.ncbi.nlm.nih.gov/pubmed/35456728 http://dx.doi.org/10.3390/microorganisms10040673 |
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