A Recombinant Turkey Herpesvirus Expressing the F Protein of Newcastle Disease Virus Genotype XII Generated by NHEJ-CRISPR/Cas9 and Cre-LoxP Systems Confers Protection against Genotype XII Challenge in Chickens

In this study, we developed a new recombinant virus rHVT-F using a Turkey herpesvirus (HVT) vector, expressing the fusion (F) protein of the genotype XII Newcastle disease virus (NDV) circulating in Peru. We evaluated the viral shedding and efficacy against the NDV genotype XII challenge in specific...

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Detalles Bibliográficos
Autores principales: Calderón, Katherine, Rojas-Neyra, Aldo, Carbajal-Lévano, Brigith, Luján-Valenzuela, Luis, Ticona, Julio, Isasi-Rivas, Gisela, Montalvan, Angela, Criollo-Orozco, Manuel, Huaccachi-Gonzáles, Edison, Tataje-Lavanda, Luis, Alvarez, Karla Lucia F., Fernández-Sánchez, Manolo, Fernández-Díaz, Manolo, Tang, Na, Yao, Yongxiu, Nair, Venugopal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030537/
https://www.ncbi.nlm.nih.gov/pubmed/35458523
http://dx.doi.org/10.3390/v14040793

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