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Implications of Dosage Deficiencies in CTCF and Cohesin on Genome Organization, Gene Expression, and Human Neurodevelopment

Properly organizing DNA within the nucleus is critical to ensure normal downstream nuclear functions. CTCF and cohesin act as major architectural proteins, working in concert to generate thousands of high-intensity chromatin loops. Due to their central role in loop formation, a massive research effo...

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Detalles Bibliográficos
Autores principales:	Cummings, Christopher T., Rowley, M. Jordan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030571/ https://www.ncbi.nlm.nih.gov/pubmed/35456389 http://dx.doi.org/10.3390/genes13040583

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