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Mapping the Key Residues within the Porcine Reproductive and Respiratory Syndrome Virus nsp1α Replicase Protein Required for Degradation of Swine Leukocyte Antigen Class I Molecules
The nonstructural protein 1α (nsp1α) of the porcine reproductive and respiratory syndrome virus (PRRSV) has been shown to target swine leukocyte antigen class I (SLA-I) for degradation, but the molecular details remain unclear. In this report, we further mapped the critical residues within nsp1α by...
Autores principales: | Liu, Yuanyuan, Gao, Peng, Zhou, Lei, Ge, Xinna, Zhang, Yongning, Guo, Xin, Han, Jun, Yang, Hanchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030574/ https://www.ncbi.nlm.nih.gov/pubmed/35458420 http://dx.doi.org/10.3390/v14040690 |
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