Cargando…

Phylogenetic Comparison of Swainsonine Biosynthetic Gene Clusters among Fungi

Swainsonine is a cytotoxic alkaloid produced by fungi. Genome sequence analyses revealed that these fungi share an orthologous gene cluster, SWN, necessary for swainsonine biosynthesis. To investigate the SWN cluster, the gene sequences and intergenic regions were assessed in organisms containing sw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neyaz, Marwa, Das, Sumanjari, Cook, Daniel, Creamer, Rebecca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030584/ https://www.ncbi.nlm.nih.gov/pubmed/35448590 http://dx.doi.org/10.3390/jof8040359

Ejemplares similares

Localization of the Swainsonine-Producing Chaetothyriales Symbiont in the Seed and Shoot Apical Meristem in Its Host Ipomoea carnea
por: Neyaz, Marwa, et al.
Publicado: (2022)

Swainsonine Biosynthesis Genes in Diverse Symbiotic and Pathogenic Fungi
por: Cook, Daniel, et al.
Publicado: (2017)

Silencing of the Transmembrane Transporter (swnT) Gene of the Fungus Slafractonia leguminicola Results in a Reduction of Mycotoxin Transport
por: Das, Sumanjari, et al.
Publicado: (2023)

Phylogenetic Patterns of Swainsonine Presence in Morning Glories
por: Quach, Quynh N., et al.
Publicado: (2022)

Transcriptional Activation of Biosynthetic Gene Clusters in Filamentous Fungi
por: Mózsik, László, et al.
Publicado: (2022)

The evolution of the gliotoxin biosynthetic gene cluster in Penicillium fungi
por: Balamurugan, Charu, et al.
Publicado: (2023)

Screening of Endophytic Fungi in Locoweed Induced by Heavy-Ion Irradiation and Study on Swainsonine Biosynthesis Pathway
por: Mo, Yanan, et al.
Publicado: (2022)

Hematological and histopathological effects of swainsonine in mouse
por: Wu, Chenchen, et al.
Publicado: (2015)

Genetic Relationships in the Toxin-Producing Fungal Endophyte, Alternaria oxytropis Using Polyketide Synthase and Non-Ribosomal Peptide Synthase Genes
por: Creamer, Rebecca, et al.
Publicado: (2021)

Improving candidate Biosynthetic Gene Clusters in fungi through reinforcement learning
por: Almeida, Hayda, et al.
Publicado: (2022)

Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi
por: Tran, Phuong Nguyen, et al.
Publicado: (2019)

Reproductive Toxicities Caused by Swainsonine from Locoweed in Mice
por: Wu, Chenchen, et al.
Publicado: (2016)

Phylogenetic classification of natural product biosynthetic gene clusters based on regulatory mechanisms
por: Rodriguez-Sanchez, Alberto C., et al.
Publicado: (2023)

Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi
por: Cacho, Ralph A., et al.
Publicado: (2015)

Effects of swainsonine on rat liver and kidney: biochemical and morphological studies
Publicado: (1985)

The Genome of Undifilum oxytropis Provides Insights into Swainsonine Biosynthesis and Locoism
por: Lu, Hao, et al.
Publicado: (2016)

Transcriptome Profiles of Alternaria oxytropis Provides Insights into Swainsonine Biosynthesis
por: Li, Xin, et al.
Publicado: (2019)

Epigenetic Activation of Silent Biosynthetic Gene Clusters in Endophytic Fungi Using Small Molecular Modifiers
por: Pillay, Lynise C., et al.
Publicado: (2022)

Potential Degradation of Swainsonine by Intracellular Enzymes of Arthrobacter sp. HW08
por: Wang, Yan, et al.
Publicado: (2013)

Swainsonine protects both murine and human haematopoietic systems from chemotherapeutic toxicity
por: Klein, J-L D, et al.
Publicado: (1999)

Swainsonine Induces Apoptosis through Mitochondrial Pathway and Caspase Activation in Goat Trophoblasts
por: Huang, Yong, et al.
Publicado: (2014)

Global analyses of biosynthetic gene clusters in phytobiomes reveal strong phylogenetic conservation of terpenes and aryl polyenes
por: Mukherjee, Arijit, et al.
Publicado: (2023)

BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs
por: Meleshko, Dmitry, et al.
Publicado: (2019)

Genome-Wide Analysis of Biosynthetic Gene Cluster Reveals Correlated Gene Loss with Absence of Usnic Acid in Lichen-Forming Fungi
por: Pizarro, David, et al.
Publicado: (2020)

Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines
por: Hamaguchi, Jun, et al.
Publicado: (2007)

Swainsonine exposure induces impairment of host immune response in pregnant BALB/c mice
por: Hu, Yanchun, et al.
Publicado: (2015)

Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1
por: Ma, Junxun, et al.
Publicado: (2018)

The plant secondary compound swainsonine reshapes gut microbiota in plateau pikas (Ochotona curzoniae)
por: Ren, Shien, et al.
Publicado: (2021)

Comparative Genomic Analysis of Ochratoxin A Biosynthetic Cluster in Producing Fungi: New Evidence of a Cyclase Gene Involvement
por: Ferrara, Massimo, et al.
Publicado: (2020)

Identification and Phylogenetic Characterization of Cobalamin Biosynthetic Genes of Ensifer adhaerens
por: Vu, Hoan Thi, et al.
Publicado: (2013)

In silico analyses of maleidride biosynthetic gene clusters
por: Williams, Katherine, et al.
Publicado: (2022)

Multiplexed mobilization and expression of biosynthetic gene clusters
por: Libis, Vincent, et al.
Publicado: (2022)

Sequence analysis of porothramycin biosynthetic gene cluster
por: Najmanova, Lucie, et al.
Publicado: (2014)

Evolution and Diversity of Biosynthetic Gene Clusters in Fusarium
por: Hoogendoorn, Koen, et al.
Publicado: (2018)

Functional Analysis of the Fusarielin Biosynthetic Gene Cluster
por: Droce, Aida, et al.
Publicado: (2016)

Mining biosynthetic gene clusters in Virgibacillus genomes
por: Othoum, Ghofran, et al.
Publicado: (2019)

Identification and heterologous expression of the globomycin biosynthetic gene cluster
por: Oves-Costales, Daniel, et al.
Publicado: (2023)

Development of Novel Formulation for Sustained Release of Drug to Prevent Swainsonine-Containing Plants Poisoning in Livestock
por: Li, Bo, et al.
Publicado: (2023)

Phylogenetic analysis of the salinipostin γ-butyrolactone gene cluster uncovers new potential for bacterial signalling-molecule diversity
por: Creamer, Kaitlin E., et al.
Publicado: (2021)

Genome Sequencing and analyses of Two Marine Fungi from the North Sea Unraveled a Plethora of Novel Biosynthetic Gene Clusters
por: Kumar, Abhishek, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_k10l5p9mfvi0joeuqa6qsdan73