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Vertebral Osteomyelitis and Infective Endocarditis Co-Infection
Many cases of vertebral osteomyelitis (VO) and infective endocarditis (IE) co-infection have been reported, and it has been recognized that attention should be paid to the possibility of both diseases co-existing during diagnosis and treatment. However, the incidence, clinical status, and outcomes o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030611/ https://www.ncbi.nlm.nih.gov/pubmed/35456361 http://dx.doi.org/10.3390/jcm11082266 |
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author | Morimoto, Tadatsugu Hirata, Hirohito Otani, Koji Nakamura, Eiichiro Miyakoshi, Naohisa Terashima, Yoshinori Wada, Kanichiro Kobayashi, Takaomi Murayama, Masatoshi Tsukamoto, Masatsugu Mawatari, Masaaki |
author_facet | Morimoto, Tadatsugu Hirata, Hirohito Otani, Koji Nakamura, Eiichiro Miyakoshi, Naohisa Terashima, Yoshinori Wada, Kanichiro Kobayashi, Takaomi Murayama, Masatoshi Tsukamoto, Masatsugu Mawatari, Masaaki |
author_sort | Morimoto, Tadatsugu |
collection | PubMed |
description | Many cases of vertebral osteomyelitis (VO) and infective endocarditis (IE) co-infection have been reported, and it has been recognized that attention should be paid to the possibility of both diseases co-existing during diagnosis and treatment. However, the incidence, clinical status, and outcomes of IE in patients with VO remain unclear. For this study, the eligibility criteria for patient recruitment included all cases of VO at the five medical university hospitals. Patients with a history of spinal surgery were excluded from this study. Echocardiography was routinely performed for all patients with VO. IE was diagnosed according to the modified Duke criteria for definite endocarditis. We analyzed demographic data, underlying conditions, clinical features, laboratory data, echocardiography, radiologic images, treatments, and outcomes. VO was diagnosed in 59 patients and IE was diagnosed in seven patients (12%). There were no significant differences in the clinical features, microorganisms, or radiographic status between the VO-IE co-infection and VO-only groups. In this study, using routine echocardiography for VO, the IE prevalence was 12%. The lack of specific clinical features and laboratory findings may hamper the diagnosis of IE. Therefore, clinicians are always required to suspect IE in patients with VO. |
format | Online Article Text |
id | pubmed-9030611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90306112022-04-23 Vertebral Osteomyelitis and Infective Endocarditis Co-Infection Morimoto, Tadatsugu Hirata, Hirohito Otani, Koji Nakamura, Eiichiro Miyakoshi, Naohisa Terashima, Yoshinori Wada, Kanichiro Kobayashi, Takaomi Murayama, Masatoshi Tsukamoto, Masatsugu Mawatari, Masaaki J Clin Med Article Many cases of vertebral osteomyelitis (VO) and infective endocarditis (IE) co-infection have been reported, and it has been recognized that attention should be paid to the possibility of both diseases co-existing during diagnosis and treatment. However, the incidence, clinical status, and outcomes of IE in patients with VO remain unclear. For this study, the eligibility criteria for patient recruitment included all cases of VO at the five medical university hospitals. Patients with a history of spinal surgery were excluded from this study. Echocardiography was routinely performed for all patients with VO. IE was diagnosed according to the modified Duke criteria for definite endocarditis. We analyzed demographic data, underlying conditions, clinical features, laboratory data, echocardiography, radiologic images, treatments, and outcomes. VO was diagnosed in 59 patients and IE was diagnosed in seven patients (12%). There were no significant differences in the clinical features, microorganisms, or radiographic status between the VO-IE co-infection and VO-only groups. In this study, using routine echocardiography for VO, the IE prevalence was 12%. The lack of specific clinical features and laboratory findings may hamper the diagnosis of IE. Therefore, clinicians are always required to suspect IE in patients with VO. MDPI 2022-04-18 /pmc/articles/PMC9030611/ /pubmed/35456361 http://dx.doi.org/10.3390/jcm11082266 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Morimoto, Tadatsugu Hirata, Hirohito Otani, Koji Nakamura, Eiichiro Miyakoshi, Naohisa Terashima, Yoshinori Wada, Kanichiro Kobayashi, Takaomi Murayama, Masatoshi Tsukamoto, Masatsugu Mawatari, Masaaki Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title | Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title_full | Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title_fullStr | Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title_full_unstemmed | Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title_short | Vertebral Osteomyelitis and Infective Endocarditis Co-Infection |
title_sort | vertebral osteomyelitis and infective endocarditis co-infection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030611/ https://www.ncbi.nlm.nih.gov/pubmed/35456361 http://dx.doi.org/10.3390/jcm11082266 |
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