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Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients

(1) Background: The aim of the present study was to evaluate our institutional outcome in tuberculum sellae meningioma (TSM) patients treated microsurgically using multiple skull base approaches, including a transcranial approach and an extended endonasal transsphenoidal approach. (2) Materials and...

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Autores principales: Alam, Shamsul, Ferini, Gianluca, Muhammad, Nur, Ahmed, Nazmin, Wakil, Abu Naim Mohammad, Islam, Kazi Mohammad Atiqul, Arifin, Mohammad Samsul, Al Mahbub, Abdullah, Habib, Riad, Mojumder, Mosiur Rahman, Vats, Atul, Chaurasia, Bipin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030651/
https://www.ncbi.nlm.nih.gov/pubmed/35454983
http://dx.doi.org/10.3390/life12040492
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author Alam, Shamsul
Ferini, Gianluca
Muhammad, Nur
Ahmed, Nazmin
Wakil, Abu Naim Mohammad
Islam, Kazi Mohammad Atiqul
Arifin, Mohammad Samsul
Al Mahbub, Abdullah
Habib, Riad
Mojumder, Mosiur Rahman
Vats, Atul
Chaurasia, Bipin
author_facet Alam, Shamsul
Ferini, Gianluca
Muhammad, Nur
Ahmed, Nazmin
Wakil, Abu Naim Mohammad
Islam, Kazi Mohammad Atiqul
Arifin, Mohammad Samsul
Al Mahbub, Abdullah
Habib, Riad
Mojumder, Mosiur Rahman
Vats, Atul
Chaurasia, Bipin
author_sort Alam, Shamsul
collection PubMed
description (1) Background: The aim of the present study was to evaluate our institutional outcome in tuberculum sellae meningioma (TSM) patients treated microsurgically using multiple skull base approaches, including a transcranial approach and an extended endonasal transsphenoidal approach. (2) Materials and Methods: This is a retrospective study that includes 34 patients with TSM. The study aimed to observe the efficacy of the different common approaches used by a single neurosurgeon. All the patients were evaluated preoperatively and during follow-up with campimetry, head CT scan, and post-contrast MRI. (3) Results: After a transcranial approach, visual acuity improved in 86.20%, was stable in 10.34%, and deteriorated in 3.45%. Through transsphenoidal surgery, vision improved in 80%, was static in 20%, and deteriorated in 0%. Transcranial approaches included pterional, mini-bifrontal basal, and supraciliary keyhole microscopic craniotomies. Gross total removal was performed in 58.82%, near total in 10.34%, and partial removal in 3.45%. The transcranial/supraciliary keyhole endoscopic-assisted approach showed a gross total removal rate of 80%, and near total in 20%. The transsphenoidal approach showed a gross total removal rate of 60%, near total in 20%, and partial removal in 20%. (4) Conclusion: Endoscopic-assisted keyhole supraciliary mini craniotomy for resection of tuberculum sellae meningioma offers low morbidity and good visual outcome. The endonasal route is preferred for the removal of TSM when they are small and midline placed. The major limitation of this approach is a narrow surgical corridor and the restriction on midline-placed lesions. Gross total removal was better achieved with mini-bifrontal basal and pterional craniotomies.
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spelling pubmed-90306512022-04-23 Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients Alam, Shamsul Ferini, Gianluca Muhammad, Nur Ahmed, Nazmin Wakil, Abu Naim Mohammad Islam, Kazi Mohammad Atiqul Arifin, Mohammad Samsul Al Mahbub, Abdullah Habib, Riad Mojumder, Mosiur Rahman Vats, Atul Chaurasia, Bipin Life (Basel) Article (1) Background: The aim of the present study was to evaluate our institutional outcome in tuberculum sellae meningioma (TSM) patients treated microsurgically using multiple skull base approaches, including a transcranial approach and an extended endonasal transsphenoidal approach. (2) Materials and Methods: This is a retrospective study that includes 34 patients with TSM. The study aimed to observe the efficacy of the different common approaches used by a single neurosurgeon. All the patients were evaluated preoperatively and during follow-up with campimetry, head CT scan, and post-contrast MRI. (3) Results: After a transcranial approach, visual acuity improved in 86.20%, was stable in 10.34%, and deteriorated in 3.45%. Through transsphenoidal surgery, vision improved in 80%, was static in 20%, and deteriorated in 0%. Transcranial approaches included pterional, mini-bifrontal basal, and supraciliary keyhole microscopic craniotomies. Gross total removal was performed in 58.82%, near total in 10.34%, and partial removal in 3.45%. The transcranial/supraciliary keyhole endoscopic-assisted approach showed a gross total removal rate of 80%, and near total in 20%. The transsphenoidal approach showed a gross total removal rate of 60%, near total in 20%, and partial removal in 20%. (4) Conclusion: Endoscopic-assisted keyhole supraciliary mini craniotomy for resection of tuberculum sellae meningioma offers low morbidity and good visual outcome. The endonasal route is preferred for the removal of TSM when they are small and midline placed. The major limitation of this approach is a narrow surgical corridor and the restriction on midline-placed lesions. Gross total removal was better achieved with mini-bifrontal basal and pterional craniotomies. MDPI 2022-03-28 /pmc/articles/PMC9030651/ /pubmed/35454983 http://dx.doi.org/10.3390/life12040492 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alam, Shamsul
Ferini, Gianluca
Muhammad, Nur
Ahmed, Nazmin
Wakil, Abu Naim Mohammad
Islam, Kazi Mohammad Atiqul
Arifin, Mohammad Samsul
Al Mahbub, Abdullah
Habib, Riad
Mojumder, Mosiur Rahman
Vats, Atul
Chaurasia, Bipin
Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title_full Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title_fullStr Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title_full_unstemmed Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title_short Skull Base Approaches for Tuberculum Sellae Meningiomas: Institutional Experience in a Series of 34 Patients
title_sort skull base approaches for tuberculum sellae meningiomas: institutional experience in a series of 34 patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030651/
https://www.ncbi.nlm.nih.gov/pubmed/35454983
http://dx.doi.org/10.3390/life12040492
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