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Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning

Improving productivity to reduce the cost of biologics manufacturing and ensure that therapeutics can reach more patients remains a major challenge faced by the biopharmaceutical industry. Chinese hamster ovary (CHO) cell lines are commonly prepared for biomanufacturing by single cell cloning post-t...

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Detalles Bibliográficos
Autores principales: He, Qin, Rehmann, Matthew S., Tian, Jun, Xu, Jianlin, Sabino, Luzmary, Vandermark, Erik, Basson, Ziev, Po, Iris, Bierilo, Kathleen, Tremml, Gabi, Rizzi, Giovanni, Langsdorf, Erik F., Qian, Nan-Xin, Borys, Michael C., Khetan, Anurag, Li, Zheng-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030702/
https://www.ncbi.nlm.nih.gov/pubmed/35447733
http://dx.doi.org/10.3390/bioengineering9040173