The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome

The development and translation of regenerative medicine approaches for the treatment of hypoplastic left heart syndrome (HLHS) provides a promising alternative to the current standard of care. We review the strategies that have been pursued to date and those that hold the greatest promise in moving...

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Detalles Bibliográficos
Autores principales: Kelly, John M., Anderson, Cole, Breuer, Christopher K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030758/
https://www.ncbi.nlm.nih.gov/pubmed/35448083
http://dx.doi.org/10.3390/jcdd9040107
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author Kelly, John M.
Anderson, Cole
Breuer, Christopher K.
author_facet Kelly, John M.
Anderson, Cole
Breuer, Christopher K.
author_sort Kelly, John M.
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description The development and translation of regenerative medicine approaches for the treatment of hypoplastic left heart syndrome (HLHS) provides a promising alternative to the current standard of care. We review the strategies that have been pursued to date and those that hold the greatest promise in moving forward. Significant challenges remain. Continued scientific advances and technological breakthroughs will be required if we are to translate this technology to the clinic and move from palliative to curative treatment.
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spelling pubmed-90307582022-04-23 The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome Kelly, John M. Anderson, Cole Breuer, Christopher K. J Cardiovasc Dev Dis Perspective The development and translation of regenerative medicine approaches for the treatment of hypoplastic left heart syndrome (HLHS) provides a promising alternative to the current standard of care. We review the strategies that have been pursued to date and those that hold the greatest promise in moving forward. Significant challenges remain. Continued scientific advances and technological breakthroughs will be required if we are to translate this technology to the clinic and move from palliative to curative treatment. MDPI 2022-04-02 /pmc/articles/PMC9030758/ /pubmed/35448083 http://dx.doi.org/10.3390/jcdd9040107 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Kelly, John M.
Anderson, Cole
Breuer, Christopher K.
The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title_full The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title_fullStr The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title_full_unstemmed The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title_short The Potential Role of Regenerative Medicine on the Future Management of Hypoplastic Left Heart Syndrome
title_sort potential role of regenerative medicine on the future management of hypoplastic left heart syndrome
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030758/
https://www.ncbi.nlm.nih.gov/pubmed/35448083
http://dx.doi.org/10.3390/jcdd9040107
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