Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients

Mitochondria alterations are present in tissues derived from patients and animal models, but no data are available for peripheral blood mononuclear cells (PBMCs) of ALS patients. This work aims to investigate mitophagy in PBMCs of sporadic (sALS) patients and how this pathway can be tuned by using s...

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Detalles Bibliográficos
Autores principales: Bordoni, Matteo, Pansarasa, Orietta, Scarian, Eveljn, Cristofani, Riccardo, Leone, Roberta, Fantini, Valentina, Garofalo, Maria, Diamanti, Luca, Bernuzzi, Stefano, Gagliardi, Stella, Carelli, Stephana, Poletti, Angelo, Cereda, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030813/
https://www.ncbi.nlm.nih.gov/pubmed/35455952
http://dx.doi.org/10.3390/cells11081272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030813/
https://www.ncbi.nlm.nih.gov/pubmed/35455952
http://dx.doi.org/10.3390/cells11081272

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