Cargando…

Longitudinal [(18)F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model

The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). Here, we investigated TSPO PET imaging and autoradiography in the frequently used GL261 glioblastoma mouse model and aimed to generate insights into the temporal evolutio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Holzgreve, Adrien, Pötter, Dennis, Brendel, Matthias, Orth, Michael, Weidner, Lorraine, Gold, Lukas, Kirchner, Maximilian A., Bartos, Laura M., Unterrainer, Lena M., Unterrainer, Marcus, Steiger, Katja, von Baumgarten, Louisa, Niyazi, Maximilian, Belka, Claus, Bartenstein, Peter, Riemenschneider, Markus J., Lauber, Kirsten, Albert, Nathalie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030822/ https://www.ncbi.nlm.nih.gov/pubmed/35453488 http://dx.doi.org/10.3390/biomedicines10040738

Ejemplares similares

TSPO PET signal using [(18)F]GE180 is associated with survival in recurrent gliomas
por: Quach, Stefanie, et al.
Publicado: (2022)

In response to: Anatomy of (18)F-GE180, a failed radioligand for the TSPO protein
por: Albert, Nathalie L., et al.
Publicado: (2020)

Increased TSPO PET signal after radiochemotherapy in IDH-wildtype glioma—indicator for treatment-induced immune activation?
por: Quach, Stefanie, et al.
Publicado: (2022)

Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma
por: Albert, Nathalie L., et al.
Publicado: (2023)

Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium
por: Deussing, Maximilian, et al.
Publicado: (2018)

Differential Spatial Distribution of TSPO or Amino Acid PET Signal and MRI Contrast Enhancement in Gliomas
por: Kaiser, Lena, et al.
Publicado: (2021)

PSMA PET Imaging in Glioblastoma: A Preclinical Evaluation and Theranostic Outlook
por: Kirchner, Maximilian A., et al.
Publicado: (2021)

TSPO imaging using the novel PET ligand [(18)F]GE-180: quantification approaches in patients with multiple sclerosis
por: Vomacka, Lena, et al.
Publicado: (2017)

High-Grade Glioma Radiation Therapy and Reirradiation Treatment Planning Using Translocator Protein Positron Emission Tomography With (18)F-GE-180
por: Fleischmann, Daniel Felix, et al.
Publicado: (2023)

Impact of TSPO Receptor Polymorphism on [(18)F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders
por: Vettermann, Franziska J., et al.
Publicado: (2021)

Can Radiomics Provide Additional Information in [(18)F]FET-Negative Gliomas?
por: von Rohr, Katharina, et al.
Publicado: (2022)

(68)Ga-EMP-100 PET/CT—a novel method for non-invasive assessment of c-MET expression in non-small cell lung cancer
por: Unterrainer, Lena M., et al.
Publicado: (2022)

Combination of pre-treatment dynamic [(18)F]FET PET radiomics and conventional clinical parameters for the survival stratification in patients with IDH-wildtype glioblastoma
por: Li, Zhicong, et al.
Publicado: (2022)

Anthracycline-induced cytotoxicity in the GL261 glioma model system
por: Tavener, Amber M., et al.
Publicado: (2021)

Detection of Splenic Tissue Using (99m)Tc-Labelled Denatured Red Blood Cells Scintigraphy—A Quantitative Single Center Analysis
por: Holzgreve, Adrien, et al.
Publicado: (2022)

Correction to: Next‑generation PET/CT imaging in meningioma—first clinical experiences using the novel SSTR‑targeting peptide [(18)F]SiTATE
por: Unterrainer, Marcus, et al.
Publicado: (2023)

Next-generation PET/CT imaging in meningioma—first clinical experiences using the novel SSTR-targeting peptide [(18)F]SiTATE
por: Unterrainer, Marcus, et al.
Publicado: (2023)

PSMA-Expression Is Highly Associated with Histological Subtypes of Renal Cell Carcinoma: Potential Implications for Theranostic Approaches
por: Bui, Vinh Ngoc, et al.
Publicado: (2023)

A therapeutic cancer vaccine against GL261 murine glioma
por: Kindy, Mark S., et al.
Publicado: (2016)

(18)F-FET PET radiomics-based survival prediction in glioblastoma patients receiving radio(chemo)therapy
por: Wiltgen, Tun, et al.
Publicado: (2022)

Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning
por: Eckenweber, Florian, et al.
Publicado: (2020)

PSMA Expression in Glioblastoma as a Basis for Theranostic Approaches: A Retrospective, Correlational Panel Study Including Immunohistochemistry, Clinical Parameters and PET Imaging
por: Holzgreve, Adrien, et al.
Publicado: (2021)

Translocator protein (18kDA) (TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages
por: Weidner, Lorraine, et al.
Publicado: (2023)

Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation
por: Fleischmann, Daniel F., et al.
Publicado: (2019)

Choline PET based dose-painting in prostate cancer - Modelling of dose effects
por: Niyazi, Maximilian, et al.
Publicado: (2010)

Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?
por: Niyazi, Maximilian, et al.
Publicado: (2015)

(18)F-FET PET Uptake Characteristics of Long-Term IDH-Wildtype Diffuse Glioma Survivors
por: Mittlmeier, Lena M., et al.
Publicado: (2021)

In Vivo Imaging of Glial Activation after Unilateral Labyrinthectomy in the Rat: A [(18)F]GE180-PET Study
por: Zwergal, Andreas, et al.
Publicado: (2017)

Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas
por: Feldman, Lisa A., et al.
Publicado: (2017)

Temporal and spatial modulation of the tumor and systemic immune response in the murine Gl261 glioma model
por: McKelvey, Kelly J., et al.
Publicado: (2020)

Towards standardization of (18)F-FET PET imaging: do we need a consistent method of background activity assessment?
por: Unterrainer, Marcus, et al.
Publicado: (2017)

18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model
por: Bartos, Laura M., et al.
Publicado: (2022)

Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model
por: Cornelison, R. Chase, et al.
Publicado: (2018)

Anti-PD-1 checkpoint blockade monotherapy in the orthotopic GL261 glioma model: the devil is in the detail
por: Tritz, Zachariah P, et al.
Publicado: (2021)

Metabolic patterns on [(18)F]FDG PET/CT in patients with unresectable stage III NSCLC undergoing chemoradiotherapy ± durvalumab maintenance treatment
por: Holzgreve, Adrien, et al.
Publicado: (2023)

Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells
por: Clark, Aaron J, et al.
Publicado: (2014)

GL261 luciferase-expressing cells elicit an anti-tumor immune response: an evaluation of murine glioma models
por: Sanchez, Victoria E., et al.
Publicado: (2020)

Unraveling response to temozolomide in preclinical GL261 glioblastoma with MRI/MRSI using radiomics and signal source extraction
por: Núñez, Luis Miguel, et al.
Publicado: (2020)

TERT-Promoter Mutational Status in Glioblastoma – Is There an Association With Amino Acid Uptake on Dynamic (18)F-FET PET?
por: Unterrainer, Marcus, et al.
Publicado: (2021)

The German version of the brief affective neuroscience personality scales including a LUST scale (BANPS–GL)
por: Fuchshuber, Jürgen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qnhbrocnbokv88btn0mdrjnmtd