Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase

KIAA1199 has a strong hyaluronidase activity in inflammatory arthritis. This study aimed to identify a drug that could reduce KIAA1199 activity and clarify its effects on inflammatory arthritis. Rat chondrosarcoma (RCS) cells were strongly stained with Alcian blue (AB). Its stainability was reduced...

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Detalles Bibliográficos
Autores principales: Koike, Hiroshi, Nishida, Yoshihiro, Shinomura, Tamayuki, Ohkawara, Bisei, Ohno, Kinji, Zhuo, Lisheng, Kimata, Koji, Ushida, Takahiro, Imagama, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030858/
https://www.ncbi.nlm.nih.gov/pubmed/35456905
http://dx.doi.org/10.3390/ijms23084089

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