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The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis

Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) are high-risk factors of diabetes development and may be caused by defective insulin secretion in pancreatic beta-cells. Glucose-stimulated insulin secretion is mediated by voltage-gated Ca(2+) (Ca(V)) channels in which the gamma-4...

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Detalles Bibliográficos
Autores principales: Wu, Rui, Karagiannopoulos, Alexandros, Eliasson, Lena, Renström, Erik, Luan, Cheng, Zhang, Enming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030882/
https://www.ncbi.nlm.nih.gov/pubmed/35453520
http://dx.doi.org/10.3390/biomedicines10040770