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Elimination of Reprogramming Transgenes Facilitates the Differentiation of Induced Pluripotent Stem Cells into Hepatocyte-like Cells and Hepatic Organoids

SIMPLE SUMMARY: The elimination of reprogramming transgenes affects the differentiation potential of human induced pluripotent stem cells (hiPSCs) at the early embryonic development stage, but not during the late stage of development into hepatocytes and hepatic organoids. Using an excisable polycis...

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Detalles Bibliográficos
Autores principales:	Jeong, Jaemin, Kim, Tae Hun, Kim, Myounghoi, Jung, Yun Kyung, Kim, Kyeong Sik, Shim, Sehwan, Jang, Hyosun, Jang, Won Il, Lee, Seung Bum, Choi, Dongho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030920/ https://www.ncbi.nlm.nih.gov/pubmed/35453693 http://dx.doi.org/10.3390/biology11040493

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