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Identification of Novel Natural Product Inhibitors against Matrix Metalloproteinase 9 Using Quantum Mechanical Fragment Molecular Orbital-Based Virtual Screening Methods

Matrix metalloproteinases (MMPs) are calcium-dependent zinc-containing endopeptidases involved in multiple cellular processes. Among the MMP isoforms, MMP-9 regulates cancer invasion, rheumatoid arthritis, and osteoarthritis by degrading extracellular matrix proteins present in the tumor microenviro...

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Detalles Bibliográficos
Autores principales:	Lim, Hocheol, Hong, Hansol, Hwang, Seonik, Kim, Song Ja, Seo, Sung Yum, No, Kyoung Tai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030947/ https://www.ncbi.nlm.nih.gov/pubmed/35457257 http://dx.doi.org/10.3390/ijms23084438

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