Encapsulation of Alpha-Lipoic Acid in Functional Hybrid Liposomes: Promising Tool for the Reduction of Cisplatin-Induced Ototoxicity

In this study, in order to address the drawback of cisplatin (CDDP)-induced ototoxicity, we propose a straightforward strategy based on the delivery of a sulfur-based antioxidant, such as lipoic acid (LA), to HEI-OC1 cells. To this aim, hybrid liposomes (LA@PCGC) with a spherical shape and a mean di...

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Detalles Bibliográficos
Autores principales: Curcio, Manuela, Cirillo, Giuseppe, Amato, Rosario, Guidotti, Lorenzo, Amantea, Diana, De Luca, Michele, Nicoletta, Fiore Pasquale, Iemma, Francesca, Garcia-Gil, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030957/
https://www.ncbi.nlm.nih.gov/pubmed/35455391
http://dx.doi.org/10.3390/ph15040394

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