Cargando…

Computational Screening of the Natural Product Osthole and Its Derivates for Anti-Inflammatory Activity

Osthole (OS) is a natural coumarin with a long history of medicinal use in a variety of diseases, such as itch and menstrual disorders. In recent years, OS has been shown to treat inflammation and reduce the expression and activity of NF-κB, although its mechanism of action is still unclear. Overexp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mosebarger, Angela, Reddi, Rambabu N., Menon, Ramkumar, Kammala, Ananth Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030959/ https://www.ncbi.nlm.nih.gov/pubmed/35454996 http://dx.doi.org/10.3390/life12040505

Ejemplares similares

Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
por: Kammala, Ananth Kumar, et al.
Publicado: (2023)

Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses
por: Callahan, Brianna N., et al.
Publicado: (2020)

Organic Anion Transporting Polypeptide 2B1 in Human Fetal Membranes: A Novel Gatekeeper for Drug Transport During Pregnancy?
por: Ganguly, Esha, et al.
Publicado: (2021)

Microfluidic technology and simulation models in studying pharmacokinetics during pregnancy
por: Kammala, Ananth K., et al.
Publicado: (2023)

Anti-Leishmania Activity of Osthole
por: Kermani, Elaheh Kordzadeh, et al.
Publicado: (2016)

Sodium Hydrogen Exchanger Regulatory Factor-1 (NHERF1) Regulates Fetal Membrane Inflammation
por: Kammala, Ananth Kumar, et al.
Publicado: (2020)

Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response
por: Shepherd, Megan C., et al.
Publicado: (2021)

Computer Aided Drug Design Approach to Screen Phytoconstituents of Adhatoda vasica as Potential Inhibitors of SARS-CoV-2 Main Protease Enzyme
por: Siva Kumar, Bathula, et al.
Publicado: (2022)

Natural products as sources of acetylcholinesterase inhibitors: Synthesis, biological activities, and molecular docking studies of osthole-based ester derivatives
por: Yu, Xiang, et al.
Publicado: (2022)

Exosomes from Ureaplasma parvum-infected ectocervical epithelial cells promote feto-maternal interface inflammation but are insufficient to cause preterm delivery
por: Tantengco, Ourlad Alzeus G., et al.
Publicado: (2022)

Development of a mouse model of ascending infection and preterm birth
por: Spencer, Nicholas R., et al.
Publicado: (2021)

Characterization of fetal microchimeric immune cells in mouse maternal hearts during physiologic and pathologic pregnancies
por: Lintao, Ryan C. V., et al.
Publicado: (2023)

Growth Inhibition and Apoptosis Induced by Osthole, A Natural Coumarin, in Hepatocellular Carcinoma
por: Zhang, Lurong, et al.
Publicado: (2012)

Bioengineering of Anti‐Inflammatory Natural Products
por: Winand, Lea, et al.
Publicado: (2020)

Efficacy of Osthole in Management of Hypoperfused Retina
por: Du, Ran, et al.
Publicado: (2018)

Testing of drugs using human feto-maternal interface organ-on-chips provide insights into pharmacokinetics and efficacy
por: Richardson, Lauren S., et al.
Publicado: (2022)

Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy
por: Sreenivasmurthy, Sravan Gopalkrishnashetty, et al.
Publicado: (2022)

Osthole inhibits bone metastasis of breast cancer
por: Wu, Chunyu, et al.
Publicado: (2017)

The fluorescence of a mercury probe based on osthol
por: Luo, Guangyan, et al.
Publicado: (2021)

Anti-Inflammatory Natural Products
por: Yang, Yifu, et al.
Publicado: (2015)

Fetal Membranes Contribute to Drug Transport across the Feto-Maternal Interface Utilizing the Breast Cancer Resistance Protein (BCRP)
por: Kammala, Ananthkumar, et al.
Publicado: (2022)

Amplification of microbial DNA from bacterial extracellular vesicles from human placenta
por: Menon, Ramkumar, et al.
Publicado: (2023)

Fluorescence spectroscopy of osthole binding to human serum albumin
por: Yang, Guang-De, et al.
Publicado: (2013)

Review on the protective activity of osthole against the pathogenesis of osteoporosis
por: Chen, Jincai, et al.
Publicado: (2023)

Anti-Cancer Activity of an Osthole Derivative, NBM-T-BMX-OS01: Targeting Vascular Endothelial Growth Factor Receptor Signaling and Angiogenesis
por: Yang, Hung-Yu, et al.
Publicado: (2013)

N-Hydroxycinnamide Derivatives of Osthole Ameliorate Hyperglycemia through Activation of AMPK and p38 MAPK
por: Lee, Wei-Hwa, et al.
Publicado: (2015)

Anti-Inflammatory Activity of Natural Products
por: Azab, Abdullatif, et al.
Publicado: (2016)

Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic
por: DuBreuil, Daniel M, et al.
Publicado: (2023)

Osthole Promotes Endochondral Ossification and Accelerates Fracture Healing in Mice
por: Zhang, Zhongrong, et al.
Publicado: (2016)

Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review
por: Shokoohinia, Yalda, et al.
Publicado: (2018)

Osthole: an overview of its sources, biological activities, and modification development
por: Sun, Mingna, et al.
Publicado: (2021)

Osthole induces necroptosis via ROS overproduction in glioma cells
por: Huangfu, Mengjie, et al.
Publicado: (2021)

Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner
por: Liu, Chuan-Hsiu, et al.
Publicado: (2023)

Synthesis, characterization, and antimicrobial evaluation of polyvinylalcohol-osthol composite films
por: GOWSIA, Ishrat, et al.
Publicado: (2022)

Protective effect of osthole on testicular ischemia/reperfusion injury in rats
por: Kocaman, Osman Hakan, et al.
Publicado: (2022)

Effects of Osthole on Inflammatory Gene Expression and Cytokine Secretion in Histamine-Induced Inflammation in the Caco-2 Cell Line
por: Kordulewska, Natalia K., et al.
Publicado: (2021)

Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice
por: Fang, Lijun, et al.
Publicado: (2021)

Fusarium Graminearum Growth Inhibition Due to Glucose Starvation Caused by Osthol
por: Shi, Zhiqi, et al.
Publicado: (2008)

p53 Is a Key Regulator for Osthole-Triggered Cancer Pathogenesis
por: Huang, Ssu-Ming, et al.
Publicado: (2014)

Osthole Attenuates Hepatic Injury in a Rodent Model of Trauma-Hemorrhage
por: Yu, Huang-Ping, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_dmvjsm4a0e4d292l3p6utqqkej