Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin

Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South envelope conformations, i.e., (N)-GTP and (S)-GTP, re...

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Detalles Bibliográficos
Autores principales: Toti, Kiran S., Jimah, John R., Salmaso, Veronica, Hinshaw, Jenny E., Jacobson, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031165/
https://www.ncbi.nlm.nih.gov/pubmed/35454173
http://dx.doi.org/10.3390/biom12040584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031165/
https://www.ncbi.nlm.nih.gov/pubmed/35454173
http://dx.doi.org/10.3390/biom12040584

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