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Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin
Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South envelope conformations, i.e., (N)-GTP and (S)-GTP, re...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031165/ https://www.ncbi.nlm.nih.gov/pubmed/35454173 http://dx.doi.org/10.3390/biom12040584 |