Cargando…
New Mutants of Epsilon Toxin from Clostridium perfringens with an Altered Receptor-Binding Site and Cell-Type Specificity
Epsilon toxin (Etx) from Clostridium perfringens is the third most potent toxin after the botulinum and tetanus toxins. Etx is the main agent of enterotoxemia in ruminants and is produced by Clostridium perfringens toxinotypes B and D, causing great economic losses. Etx selectively binds to target c...
Autores principales: | Dorca-Arévalo, Jonatan, Gómez de Aranda, Inmaculada, Blasi, Juan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031233/ https://www.ncbi.nlm.nih.gov/pubmed/35448898 http://dx.doi.org/10.3390/toxins14040288 |
Ejemplares similares
-
Clostridium Perfringens Epsilon Toxin Binds to Membrane Lipids and Its Cytotoxic Action Depends on Sulfatide
por: Gil, Carles, et al.
Publicado: (2015) -
Lung endothelial cells are sensitive to epsilon toxin from Clostridium perfringens
por: Dorca-Arévalo, Jonatan, et al.
Publicado: (2020) -
Correlation between In Vitro Cytotoxicity and In Vivo Lethal Activity in Mice of Epsilon Toxin Mutants from Clostridium perfringens
por: Dorca-Arévalo, Jonatan, et al.
Publicado: (2014) -
The pore structure of Clostridium perfringens epsilon toxin
por: Savva, Christos G., et al.
Publicado: (2019) -
Clostridium perfringens Epsilon Toxin Binds to and Kills Primary Human Lymphocytes
por: Shetty, Samantha V., et al.
Publicado: (2023)