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GABA and Fermented Curcuma longa L. Extract Enriched with GABA Ameliorate Obesity through Nox4-IRE1α Sulfonation-RIDD-SIRT1 Decay Axis in High-Fat Diet-Induced Obese Mice

Gamma-aminobutyric acid (GABA) is a natural amino acid with antioxidant activity and is often considered to have therapeutic potential against obesity. Obesity has long been linked to ROS and ER stress, but the effect of GABA on the ROS-associated ER stress axis has not been thoroughly explored. Thu...

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Detalles Bibliográficos
Autores principales: Lee, Hwa-Young, Lee, Geum-Hwa, Hoang, The-Hiep, Kim, Yu-Mi, Jang, Gi-Hyun, Seok, Chang-Hwan, Gwak, Yun-Geum-Sang, Lim, Junghyun, Kim, Junghyun, Chae, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031358/
https://www.ncbi.nlm.nih.gov/pubmed/35458241
http://dx.doi.org/10.3390/nu14081680