Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma

SIMPLE SUMMARY: There are currently few treatment options for individuals diagnosed with anaplastic thyroid carcinoma (ATC). Using four distinct ATC cell lines, we screened over 1500 anti-cancer agents and FDA-approved drugs. The initial screen and secondary confirmation testing identified 40 agents...

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Detalles Bibliográficos
Autores principales: Bergdorf, Kensey, Bauer, Joshua A., Westover, David, Phifer, Courtney, Murphy, Barbara, Tyson, Darren R., Lee, Ethan, Weiss, Vivian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031362/
https://www.ncbi.nlm.nih.gov/pubmed/35454763
http://dx.doi.org/10.3390/cancers14081855

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