How Do Point Mutations Enhancing the Basic Character of the RBDs of SARS-CoV-2 Variants Affect Their Transmissibility and Infectivity Capacities?

The spread of SARS-CoV-2 variants in the population depends on their ability to anchor the ACE2 receptor in the host cells. Differences in the electrostatic potentials of the spike protein RBD (electropositive/basic) and ACE2 receptor (electronegative/acidic) play a key role in both the rapprochemen...

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Detalles Bibliográficos
Autores principales: Barre, Annick, Klonjkowski, Bernard, Benoist, Hervé, Rougé, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031512/
https://www.ncbi.nlm.nih.gov/pubmed/35458513
http://dx.doi.org/10.3390/v14040783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031512/
https://www.ncbi.nlm.nih.gov/pubmed/35458513
http://dx.doi.org/10.3390/v14040783

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