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Phase I Targeted Combination Trial of Sorafenib and GW5074 in Patients with Advanced Refractory Solid Tumors
Background: Combination therapy with the administration of GW5074 and sorafenib significantly induced necrotic death in various cancer cells in vivo, as well as prolonging the survival of an animal disease model due to significant suppression of the primary and metastatic lesions. We sought to deter...
Autores principales: | Kao, Chien-Chang, Ho, Ching-Liang, Yang, Ming-Hsin, Tsai, Yi-Ta, Liu, Shu-Yu, Chang, Ping-Ying, Wu, Yi-Ying, Chen, Jia-Hong, Huang, Tzu-Chuan, Yehn, Ren-Hua, Dai, Ming-Shen, Chen, Yeu-Chin, Sun, Guang-Huan, Cha, Tai-Lung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031611/ https://www.ncbi.nlm.nih.gov/pubmed/35456276 http://dx.doi.org/10.3390/jcm11082183 |
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